Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763665 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1POLB | |
| SCHEMBL3824646 | 0.77 | CYP3A4 (0.40) | ALDH1A1ADRA2BL3MBTL1LMNAGAA | |
| SCHEMBL8136765 | 0.77 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19HDAC3HDAC1 | |
| SCHEMBL2846218 | 0.76 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19HDAC3HDAC1 | |
| SCHEMBL31172404 | 0.76 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19HDAC3HDAC1 | |
| SCHEMBL29684634 | 0.76 | CYP1A2 (0.66) | CYP1A2CYP2C9CYP2C19HDAC3HDAC1 | |
| SCHEMBL1029928 | 0.76 | CYP1A2 (0.66) | CYP1A2CYP2C9CYP2C19HDAC3HDAC1 | |
| SCHEMBL23352277 | 0.75 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19KDM4ELMNA | |
| SCHEMBL13537676 | 0.73 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19HDAC3HDAC1 | |
| SCHEMBL10812034 | 0.73 | ADORA2A (0.51) | CYP1A2CYP2C9CYP2C19ALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141065-A2 | (1,2-BENZISOTHIAZOL-3-YL)(THIO)CARBAMATES AND (1,2-BENZISOTHIAZOL-3-YL)(THIO)OXAMATES AND THE OXIDATION FORMS THEREOF FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |
| EP-2123159-A1 | (1,2-Benzisothiazol-3-yl)(thio)carbamates and (1,2-Benzisothiazol-3-yl)(thio)oxamates and their oxidation forms as pesticides | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |