Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482237 | 0.86 | MEN1 (0.46) | MEN1KMT2AEGFRTDP1TP53 | |
| SCHEMBL3481548 | 0.84 | MEN1 (0.47) | MEN1KMT2AEGFRTDP1TP53 | |
| SCHEMBL5165060 | 0.82 | MEN1 (0.44) | MEN1KMT2AEGFRTDP1ALDH1A1 | |
| SCHEMBL5165052 | 0.82 | MEN1 (0.44) | MEN1KMT2AEGFRTDP1ALDH1A1 | |
| SCHEMBL30953546 | 0.80 | MEN1 (0.63) | MEN1KMT2ARELATRPA1TUBB4A | |
| SCHEMBL1171600 | 0.80 | EGFR (0.44) | MEN1KMT2AEGFRTDP1ALDH1A1 | |
| SCHEMBL1171601 | 0.80 | EGFR (0.44) | MEN1KMT2AEGFRTDP1ALDH1A1 | |
| SCHEMBL3481567 | 0.79 | MEN1 (0.48) | MEN1KMT2AEGFRTDP1RELA | |
| SCHEMBL4264101 | 0.79 | EGFR (0.44) | MEN1KMT2AEGFRTDP1TP53 | |
| SCHEMBL2787091 | 0.79 | EGFR (0.44) | MEN1KMT2AEGFRTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280508-B1 | SKIN CARE COMPOSITION | JOHNSON & JOHNSON CONSUMER (US) | 2009-08-12 | — | — | EP | disclosed |