Sugi Predict

Sugi Predict / Compounds / SCHEMBL5165060

SCHEMBL5165060

SCHEMBL5165060

CCCCCC(C=Cc1ccccc1)OC=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ LMNA P02545 2/20 0.40
▸ EGFR P00533 1/20 0.40
▸ TDP1 Q9NUW8 2/20 0.39
▸ TSHR P16473 1/20 0.37
▸ HDAC3 O15379 2/20 0.37
▸ HDAC4 P56524 1/20 0.37
▸ HDAC1 Q13547 1/20 0.37
▸ HDAC7 Q8WUI4 1/20 0.37
▸ HDAC2 Q92769 1/20 0.37
▸ HDAC10 Q969S8 1/20 0.37
▸ HDAC11 Q96DB2 1/20 0.37
▸ HDAC8 Q9BY41 1/20 0.37
▸ HDAC6 Q9UBN7 1/20 0.37
▸ HDAC9 Q9UKV0 1/20 0.37
▸ HDAC5 Q9UQL6 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.35
▸ RELA Q04206 1/20 0.35
▸ CNR2 P34972 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5165052 1.00 MEN1 (0.44) MEN1KMT2ALMNAEGFRTDP1
SCHEMBL3481548 0.82 MEN1 (0.47) MEN1KMT2ALMNAEGFRTDP1
SCHEMBL3814977 0.82 MEN1 (0.47) MEN1KMT2ALMNAEGFRTDP1
SCHEMBL3482237 0.81 MEN1 (0.46) MEN1KMT2ALMNAEGFRTDP1
SCHEMBL1171600 0.80 EGFR (0.44) MEN1KMT2ALMNAEGFRTDP1
SCHEMBL1171601 0.80 EGFR (0.44) MEN1KMT2ALMNAEGFRTDP1
SCHEMBL3481567 0.77 MEN1 (0.48) MEN1KMT2ALMNAEGFRTDP1
SCHEMBL1220655 0.77 LMNA (0.43) MEN1KMT2ALMNAEGFRTDP1
SCHEMBL3257160 0.76 ALDH1A1 (0.41) MEN1KMT2ALMNAEGFRTDP1
SCHEMBL3257159 0.76 ALDH1A1 (0.41) MEN1KMT2ALMNAEGFRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4518647-A1 WASP PEST MANAGEMENT SYSTEM Toner, Daradh (IE) 2025-03-12 — — EP disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 — — US disclosed
WO-2023214095-A1 WASP PEST MANAGEMENT SYSTEM TONER DARADH (IE) 2023-11-09 — — WO disclosed
EP-3416729-B1 PRO-FRAGRANCE COMPOSITION AQDOT LTD (GB) 2023-09-20 — — EP disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 — — US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 — — EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 — — US disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 — — US disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 — — EP disclosed
US-10695277-B2 Pro-fragrance composition AQDOT LIMITED (GB) 2020-06-30 — — US disclosed
US-20170143022-A1 Compositions Incorporating an Umami Flavor Agent SENOMYX INC (US) 2017-05-25 — — US disclosed
WO-2017075257-A2 HIGH INTENSITY SWEETENERS SENOMYX, INC. (US) 2017-05-04 — — WO disclosed
US-20170119032-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED 2017-05-04 — — US disclosed
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2017-04-06 — — US disclosed
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION SENOMYX INC (US) 2017-03-30 — — US disclosed
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF SENOMYX INC (US) 2016-12-29 — — US disclosed
US-8539631-B2 Roller for providing benefits to fabric THE PROCTER & GAMBLE COMPANY (US) 2013-09-24 — — US disclosed
EP-1765139-A1 ROLLER FOR PROVIDING BENEFITS TO FABRIC The Procter and Gamble Company (US) 2007-03-28 — — EP disclosed
WO-2006010087-A1 ROLLER FOR PROVIDING BENEFITS TO FABRIC THE PROCTER & GAMBLE COMPANY (US) 2006-01-26 — — WO disclosed
US-20060005333-A1 Roller for providing benefits to fabric PROCTER & GAMBLE COMPANY, THE 2006-01-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 MEN1 2644/4885KMT2A 2697/4885LMNA 4834/4885
US-20170119032-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 MEN1 2644/4885KMT2A 2697/4885LMNA 4834/4885
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF TAS2R5, TAS1R1, TAS2R1 MEN1 3045/4885KMT2A 2214/4885LMNA 4440/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 MEN1 2644/4885KMT2A 2697/4885LMNA 4834/4885
US-20170143022-A1 Compositions Incorporating an Umami Flavor Agent TAS2R8, TAS2R45, TAS2R40 MEN1 2743/4885KMT2A 2393/4885LMNA 2068/4885
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION TRPA1, PDE6G, PDE6D MEN1 404/4885KMT2A 4022/4885LMNA 4541/4885
US-20210227863-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 MEN1 2644/4885KMT2A 2697/4885LMNA 4834/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 MEN1 2644/4885KMT2A 2697/4885LMNA 4834/4885
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 MEN1 1247/4885KMT2A 4178/4885LMNA 4164/4885
US-10695277-B2 Pro-fragrance composition COPS5, COPS8, CBR3 MEN1 2954/4885KMT2A 3712/4885LMNA 2903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.