Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 11/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815033 | 0.85 | PRKCQ (0.57) | PRKCQKMT2AMAPTKDM4ELMNA | |
| SCHEMBL3816754 | 0.82 | PRKCQ (0.57) | PRKCQKMT2AMAPTKDM4ELMNA | |
| SCHEMBL3812825 | 0.78 | KMT2A (0.57) | PRKCQKMT2AMAPTKDM4ELMNA | |
| SCHEMBL13720652 | 0.74 | PRKCQ (1.00) | PRKCQ | |
| SCHEMBL13794832 | 0.72 | PRKCQ (1.00) | PRKCQ | |
| SCHEMBL4479341 | 0.71 | KMT2A (0.57) | PRKCQKMT2AMAPTKDM4ELMNA | |
| SCHEMBL3816247 | 0.69 | PRKCQ (0.57) | PRKCQKMT2ANPC1MITFRAB9A | |
| SCHEMBL3818551 | 0.69 | SMN1; SMN2 (0.47) | PRKCQKMT2AMAPTLMNANPC1 | |
| SCHEMBL3819073 | 0.69 | PKM (0.48) | PRKCQKMT2AMAPTNPC1MITF | |
| SCHEMBL3812387 | 0.69 | PRKCQ (0.51) | PRKCQKMT2AMAPTPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590334-B1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF PKC-THETA | BOEHRINGER INGELHEIM PHARMA (US) | 2009-08-19 | — | — | EP | disclosed |