Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 16/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306992 | 0.88 | ACKR3 (0.46) | ACKR3P2RX3F10F7 | |
| SCHEMBL1306993 | 0.88 | ACKR3 (0.46) | ACKR3P2RX3F10F7 | |
| SCHEMBL1306990 | 0.88 | ACKR3 (0.46) | ACKR3P2RX3F10F7 | |
| SCHEMBL3833312 | 0.81 | P2RX3 (0.44) | P2RX3 | |
| SCHEMBL1305726 | 0.79 | P2RX3 (0.52) | ACKR3P2RX3 | |
| SCHEMBL1305724 | 0.79 | P2RX3 (0.52) | ACKR3P2RX3 | |
| SCHEMBL3831385 | 0.78 | TSHR (0.38) | P2RX3 | |
| SCHEMBL3816350 | 0.77 | SLC6A4 (0.40) | P2RX3 | |
| SCHEMBL1305459 | 0.76 | P2RX3 (0.60) | ACKR3P2RX3F10F7 | |
| SCHEMBL3834922 | 0.75 | P2RX3 (0.39) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089354-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008054154-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |