Saccharin

Saccharin

SCHEMBL3816

O=C1NS(=O)(=O)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 1.00
CA9 Q16790 7/20 1.00
CA2 P00918 5/20 1.00
CA1 P00915 4/20 1.00
CA7 P43166 3/20 1.00
KDM4E B2RXH2 3/20 1.00
CA4 P22748 2/20 1.00
USP2 O75604 1/20 1.00
LMNA P02545 1/20 1.00
BCHE P06276 1/20 1.00
CA6 P23280 1/20 1.00
CA5A P35218 1/20 1.00
KMT2A Q03164 1/20 1.00
CA14 Q9ULX7 1/20 1.00
CA5B Q9Y2D0 1/20 1.00
ALDH1A1 P00352 3/20 0.59
RET P07949 2/20 0.55
GRK5 P34947 2/20 0.55
TYRO3 Q06418 2/20 0.55
DYRK1B Q9Y463 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL6033672 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL6049140 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL4199164 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL7073018 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL4777123 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL588640 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL29358404 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL29191365 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL9463482 0.98 CA12 (0.96) CA12CA9CA2CA1CA7
Saccharin SCHEMBL435836 0.98 CA12 (0.96) CA12CA9CA2CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 226965 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363403-B1 PROCESSES FOR THE PREPARATION OF (S)-2-(4-CHLORO-2-METHOXYPHENYL)-2-((3-METHOXY-5-(METHYLSULFONYL)PHENYL)AMINO)-1-(1H-INDOL-3-YL)ETHENONE DERIVATIVES UNIV LEUVEN KATH (BE) 2026-05-27 EP claimed
CN-122080093-A Compounds effective in treating liver toxicity and fatty liver disease and uses thereof 2026-05-26 CN claimed
CN-122081908-A Alkaline chemical nickel surface treatment method for pure aluminum or aluminum alloy 2026-05-26 CN claimed
CN-122075589-A Preparation method of pelvic inflammation eliminating oral liquid 2026-05-26 CN claimed
US-12636289-B2 Lamotrigine oral liquid suspension and use thereof OWP Pharmaceuticals, Inc. (US) 2026-05-26 US claimed
CN-122075328-A Dentifrice with whitening, tooth stain removing and anti-inflammatory effects and preparation method thereof 2026-05-26 CN claimed
CN-122075376-A An oral cavity cough liquid for preventing and treating stomatocace and refreshing breath, and its preparation method 2026-05-26 CN claimed
CN-122082054-A Electrolysis additive composition and application method thereof 2026-05-26 CN claimed
CN-121802410-B Electroplating Ni-P-Fe on surface of aluminum nitride substrate2O3Method for producing a PTFE composite lubricant layer 深圳市好利时实业有限公司 2026-05-22 CN claimed
WO-2026105122-A1 SUGAR-REDUCED COCOA FOOD PRODUCTS COMPRISING A SWEET PROTEIN AMAI PROTEINS LTD (IL) 2026-05-21 WO claimed
US-3962417-A BACILLUS ACIDOPHILIOS HOWELL CHARLES J 1976-06-08 US claimed
US-3957772-A PROCESS FOR THE PREPARATION OF 4-HYDROXY-3-(5-METHYL-3-ISOXAZOLYLCARBAMOYL)-2-METHYL-2H-1,2-BENZOTHIAZINE 1,1-DIOXIDE WARNER-LAMBERT COMPANY (US) 1976-05-18 US claimed
US-3957491-A Silver halide photographic material containing an organic compound having a covalent nitrogen-halogen bond as sensitizer FUJI PHOTO FILM CO., LTD. (JA) 1976-05-18 US claimed
US-3954962-A VISCOSITY ADJUSTERS, NON-AQUEOUS Tripp, Alan R. (US) 1976-05-04 US claimed
US-3953304-A ACETYLENIC DI-PYRIDINIUM COMPOUND DART INDUSTRIES INC. (US) 1976-04-27 US claimed
US-3948659-A BLEACHING FUJI PHOTO FILM CO., LTD. (JA) 1976-04-06 US claimed
US-3943258-A L-ASPARTYL-L-PHENYLALANINE METHYL ESTER GENERAL FOODS CORPORATION (US) 1976-03-09 US claimed
US-3939286-A Process for oxidizing and hydrolyzing plant organic matter particles to increase the digestability thereof by ruminants JELKS JAMES W 1976-02-17 US claimed
US-3933508-A ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, BINDER FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US claimed
US-3933748-A Anaerobic adhesive containing tetrahydroquinoline and benzosulfimide OKURA KOGYA KABUSHIKI KAISHA (JA) 1976-01-20 US claimed