Saccharin

Saccharin

SCHEMBL588640

O=C1NS(=O)(=O)c2ccccc21.O=C1NS(=O)(=O)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 1.00
CA9 Q16790 7/20 1.00
CA2 P00918 5/20 1.00
CA1 P00915 4/20 1.00
CA7 P43166 3/20 1.00
KDM4E B2RXH2 3/20 1.00
CA4 P22748 2/20 1.00
USP2 O75604 1/20 1.00
LMNA P02545 1/20 1.00
BCHE P06276 1/20 1.00
CA6 P23280 1/20 1.00
CA5A P35218 1/20 1.00
KMT2A Q03164 1/20 1.00
CA14 Q9ULX7 1/20 1.00
CA5B Q9Y2D0 1/20 1.00
ALDH1A1 P00352 3/20 0.59
RET P07949 2/20 0.55
GRK5 P34947 2/20 0.55
TYRO3 Q06418 2/20 0.55
DYRK1B Q9Y463 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL6033672 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL6049140 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL4199164 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL7073018 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL4777123 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL29358404 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL29191365 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL3816 1.00 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL9463482 0.98 CA12 (0.96) CA12CA9CA2CA1CA7
Saccharin SCHEMBL435836 0.98 CA12 (0.96) CA12CA9CA2CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024102605-A1 CONJUGATION OF SACCHARIDE ANTIGENS USING ACETOXYBOROHYDRIDES MERCK SHARP & DOHME LLC (US) 2024-05-16 WO claimed
CN-109925277-A A kind of polysaccharide-based temperature-responsive nanogel and preparation method and application 上海交通大学医学院附属第九人民医院 2019-06-25 CN claimed
CN-105348410-B One kind polysaccharide containing iodine and its synthetic method and application 中山大学 2019-02-26 CN claimed
EP-3394197-A1 METHOD FOR PRODUCING COLORLESS AND AGING-RESISTANT, POLYACRYLATE-BASED PRESSURE-SENSITIVE ADHESIVE COMPOUNDS tesa SE (DE) 2018-10-31 EP claimed
EP-1506007-B1 MUCOSAL COMBINATION VACCINES FOR BACTERIAL MENINGITIS NOVARTIS VACCINES & DIAGNOSTIC (IT) 2011-06-22 EP claimed
CN-101665542-A Preparation method of sulfated polysaccharide UNIV WUHAN 2010-03-10 CN claimed
US-20060263390-A1 Modified saccharides, conjugates thereof, and their manufacture GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2006-11-23 US claimed
EP-1534342-B1 MODIFIED SACCHARIDES, CONJUGATES THEREOF, AND THEIR MANUFACTURE CHIRON SRL (IT) 2006-03-08 EP claimed
EP-1534342-A1 MODIFIED SACCHARIDES, CONJUGATES THEREOF, AND THEIR MANUFACTURE Chiron SRL. (IT) 2005-06-01 EP claimed
WO-2004019992-A1 MODIFIED SACCHARIDES, CONJUGATES THEREOF, AND THEIR MANUFACTURE CHIRON SRL (IT) 2004-03-11 WO claimed
CN-118146401-A Passion fruit dietary fiber/nano zinc oxide composite film and preparation method and application thereof 桂林理工大学 2024-06-07 CN disclosed
WO-2024102605-A1 CONJUGATION OF SACCHARIDE ANTIGENS USING ACETOXYBOROHYDRIDES MERCK SHARP & DOHME LLC (US) 2024-05-16 WO disclosed
CN-117339555-A Integral monolithic activated carbon adsorption material and application thereof 张家港安储科技有限公司 2024-01-05 CN disclosed
CN-114990168-B Composition prepared by fermenting sour cherry and having good health care function and application of composition in health field 灶灶科技有限公司 2023-05-26 CN disclosed
US-11169101-B2 Oligosaccharide compositions and methods of use thereof KALEIDO BIOSCIENCES, INC. (US) 2021-11-09 US disclosed
US-5556781-A DNA encoding enzyme, recombinant DNA and enzyme, transformant, and their preparations and uses KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1996-09-17 US disclosed
US-4965069-A ALTERED PHYSICAL OR CHEMICAL STRUCTURE BY MEANS OF OXIDIZING AGENTS CYTOGEN CORPORATION 1990-10-23 US disclosed
US-4944952-A Using galactosidase KABUSHIKI KAISHA YAKULT HONSHA (JP) 1990-07-31 US disclosed
US-4853326-A OXIDATION OF OLIGOSACCHARIDES WITH PERIODIC ACID CYTOGEN CORPORATON (US) 1989-08-01 US disclosed
US-4339239-A TEXTILE DYE BATHS MERCK & CO., INC. (US) 1982-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11169101-B2 Oligosaccharide compositions and methods of use thereof OGT, FUT5, FUT6 CA12 257/4885CA9 403/4885CA2 2185/4885
US-20060263390-A1 Modified saccharides, conjugates thereof, and their manufacture C9, B3GNT2, OGA CA12 137/4885CA9 658/4885CA2 2867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.