SCHEMBL3816223

SCHEMBL3816223

CSC[C@@H](N)CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21690262 1.00
SCHEMBL23384595 1.00
SCHEMBL1256549 0.79 ANPEP (0.50)
SCHEMBL13254782 0.79 ANPEP (0.50)
SCHEMBL289172 0.79 ANPEP (0.50)
SCHEMBL16187037 0.79 ANPEP (0.50)
SCHEMBL288510 0.78 SLC22A6 (0.50)
SCHEMBL288882 0.76 FOLH1 (0.50)
Acetic Acid SCHEMBL2595033 0.76 SLC22A6 (0.43)
SCHEMBL28799207 0.75 SLC22A6 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230000996-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF THE JOHNS HOPKINS UNIVERSITY 2023-01-05 US disclosed
US-11066416-B2 Rapafucin derivative compounds and methods of use thereof THE JOHNS HOPKINS UNIVERSITY (US) 2021-07-20 US disclosed
WO-2021067439-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF THE JOHNS HOPKINS UNIVERSITY (US) 2021-04-08 WO disclosed
US-20210094933-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF THE JOHNS HOPKINS UNIVERSITY 2021-04-01 US disclosed
US-20200040004-A1 RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF RAPAFUSYN PHARMACEUTICALS, INC. 2020-02-06 US disclosed
EP-2934563-A1 ANTIMICROBIAL COMPOUNDS, THEIR SYNTHESIS AND APPLICATIONS THEREOF Jawaharlal Nehru Centre for Advanced Scientific Research (IN) 2015-10-28 EP disclosed
WO-2014097178-A1 ANTIMICROBIAL COMPOUNDS, THEIR SYNTHESIS AND APPLICATIONS THEREOF JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2014-06-26 WO disclosed
WO-2009132861-A2 AQUEOUS, ACID BATH AND METHOD FOR THE ELECTROLYTIC DEPOSITION OF COPPER ATOTECH DEUTSCHLAND GMBH (DE) 2009-11-05 WO disclosed