Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.51 |
| ▸ | ITGAV | P06756 | 8/20 | 0.51 |
| ▸ | DRD2 | P14416 | 7/20 | 0.42 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496378 | 0.90 | ITGB3 (0.42) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL383374 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BITGAV | |
| SCHEMBL381829 | 0.85 | ITGB3 (0.57) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL6796554 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL6800147 | 0.84 | ITGB3 (0.45) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL28747046 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL382962 | 0.84 | ITGB3 (0.49) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL383160 | 0.83 | ITGAV (0.58) | ITGB3ITGA2BITGAV | |
| SCHEMBL382446 | 0.83 | ITGAV (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL382134 | 0.83 | ITGB3 (0.73) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |