Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL3812346 | 0.92 | KDM4E (0.52) | CYP3A4 | |
| SCHEMBL3810344 | 0.86 | TAAR1 (0.49) | TAAR1HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL25519810 | 0.84 | TAAR1 (0.61) | TAAR1HTR2AHTR2CHTR2BCALM1 | |
| SCHEMBL30101707 | 0.84 | TAAR1 (0.61) | TAAR1HTR2AHTR2CHTR2BCALM1 | |
| SCHEMBL27281480 | 0.81 | CYP3A4 (0.57) | TAAR1CALM1CYP3A4 | |
| SCHEMBL3816453 | 0.80 | TAAR1 (0.56) | TAAR1CALM1CYP3A4SLC6A4 | |
| SCHEMBL4066482 | 0.78 | TAAR1 (0.61) | TAAR1CALM1CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL3809815 | 0.77 | BIRC5 (0.43) | TAAR1HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL3813266 | 0.76 | BIRC5 (0.42) | TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL3809994 | 0.76 | TAAR1 (0.48) | TAAR1CALM1CYP3A4SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |