Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777138 | 0.85 | CYP3A4 (0.58) | TAAR1CALM1CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL29644736 | 0.83 | TAAR1 (0.67) | TAAR1CALM1CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL834910 | 0.83 | TAAR1 (0.67) | TAAR1CALM1CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL3817676 | 0.80 | TAAR1 (0.51) | TAAR1CALM1CYP3A4SLC6A4 | |
| SCHEMBL3812391 | 0.80 | CYP3A4 (0.54) | TAAR1CALM1CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL79785 | 0.80 | CALM1 (0.64) | TAAR1CALM1CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL108087 | 0.78 | TAAR1 (0.77) | TAAR1CALM1CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL5809247 | 0.78 | CALM1 (0.62) | TAAR1CALM1CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL30101936 | 0.78 | CALM1 (0.62) | TAAR1CALM1CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL4066482 | 0.78 | TAAR1 (0.61) | TAAR1CALM1CYP3A4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2067278-A | — | — | None | — | — | JP | disclosed |
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |
| JP-H0267278-A | BENZODIOXOLE DERIVATIVE | EISAI CO LTD | 1990-03-07 | — | — | JP | disclosed |