Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83065 | 1.00 | AKR1C3 (0.55) | AKR1C3ABCG2AKR1C1ALDH1A1RECQL | |
| SCHEMBL3818255 | 1.00 | AKR1C3 (0.55) | AKR1C3ABCG2AKR1C1ALDH1A1RECQL | |
| SCHEMBL8351839 | 0.98 | AKR1C3 (0.53) | AKR1C3ABCG2AKR1C1ALDH1A1RECQL | |
| Hydrochloric Acid SCHEMBL10437231 | 0.98 | AKR1C3 (0.53) | AKR1C3ABCG2AKR1C1ALDH1A1RECQL | |
| Ammonia Solution, Strong SCHEMBL4743624 | 0.98 | ABCG2 (0.56) | AKR1C3ABCG2AKR1C1ALDH1A1RECQL | |
| Acrylic Acid SCHEMBL2468603 | 0.91 | ABCG2 (0.48) | AKR1C3ABCG2AKR1C1ALDH1A1RECQL | |
| Cyanamide SCHEMBL5277769 | 0.89 | MCL1 (0.47) | AKR1C3ABCG2AKR1C1ALDH1A1RECQL | |
| Tert-Butylbenzene SCHEMBL31552779 | 0.88 | ABCG2 (0.46) | AKR1C3ABCG2AKR1C1ALDH1A1RECQL | |
| Monoethanolamine SCHEMBL30202395 | 0.88 | ABCG2 (0.46) | AKR1C3ABCG2AKR1C1ALDH1A1RECQL | |
| SCHEMBL9103420 | 0.88 | ABCG2 (0.54) | AKR1C3ABCG2AKR1C1ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867776-A | Coated aramid pulp for rubber reinforcement | 巴斯夫欧洲公司 | 2022-08-05 | — | — | CN | disclosed |
| EP-2275398-B1 | APPLICATION OF AN IRIDIUM COMPLEX IN ASYMMETRIC CATALYTIC HYDROGENATION OF AN UNSATURATED CARBOXYLIC ACID | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2016-05-04 | — | — | EP | disclosed |
| US-8692018-B2 | Application of iridium complexes in asymmetric catalytic hydrogenation of unsaturated carboxylic acids | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2014-04-08 | — | — | US | disclosed |
| US-8692018-B2 | Application of iridium complexes in asymmetric catalytic hydrogenation of unsaturated carboxylic acids | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2014-04-08 | — | — | US | disclosed |
| US-20140056834-A1 | COSMETIC COMPOSITION COMPRISING CHRYSOPHANOL AS ACTIVE INGREDIENT FOR SKIN WHITENING | PUKYONG NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2014-02-27 | — | — | US | disclosed |
| EP-2561007-A1 | PHOTOALIGNING MATERIAL | Rolic AG (CH) | 2013-02-27 | — | — | EP | disclosed |
| US-20110092732-A1 | APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-04-21 | — | — | US | disclosed |
| US-20110092732-A1 | APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS | Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2011-04-21 | — | — | US | disclosed |
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
| CN-1543451-A | Receptor modulators activated by peroxizonal proliferators (ppar) | — | 2004-11-03 | — | — | CN | disclosed |
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092732-A1 | APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS | HDHD5, ELOVL5, FASN | AKR1C3 740/4885ABCG2 2157/4885AKR1C1 645/4885 |
| US-20140056834-A1 | COSMETIC COMPOSITION COMPRISING CHRYSOPHANOL AS ACTIVE INGREDIENT FOR SKIN WHITENING | TYR, MITF, MC1R | AKR1C3 1665/4885ABCG2 2178/4885AKR1C1 2385/4885 |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | AKR1C3 389/4885ABCG2 1309/4885AKR1C1 659/4885 |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | AKR1C3 367/4885ABCG2 1215/4885AKR1C1 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.