SCHEMBL3818356

SCHEMBL3818356

O=C1CCCCCCCCCC/C=C\CCO1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.56
CA9 Q16790 2/20 0.56
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
ATM Q13315 2/20 0.35
SHH Q15465 3/20 0.35
GLS O94925 2/20 0.33
TRIM24 O15164 1/20 0.31
TRIM33 Q9UPN9 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC10 Q969S8 1/20 0.30
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15624126 1.00 CA1 (0.56) CA1CA9ALDH1A1LMNATP53
SCHEMBL7948590 1.00 CA1 (0.56) CA1CA9ALDH1A1LMNATP53
SCHEMBL14232322 1.00 CA1 (0.56) CA1CA9ALDH1A1LMNATP53
SCHEMBL7948593 1.00 CA1 (0.56) CA1CA9ALDH1A1LMNATP53
SCHEMBL7459795 1.00 CA1 (0.56) CA1CA9ALDH1A1LMNATP53
SCHEMBL14125364 1.00 CA1 (0.56) CA1CA9ALDH1A1LMNATP53
SCHEMBL7460976 1.00 CA1 (0.56) CA1CA9ALDH1A1LMNATP53
SCHEMBL11137251 1.00 CA1 (0.56) CA1CA9ALDH1A1LMNATP53
SCHEMBL20590515 1.00 CA1 (0.56) CA1CA9ALDH1A1LMNATP53
SCHEMBL10442478 1.00 CA1 (0.56) CA1CA9ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441954-B2 Powdery, musky odorant macrocycles FIRMENICH SA (CH) 2025-10-14 US claimed
EP-4312962-B1 POWDERY, MUSKY ODORANT MACROCYCLES AND THEIR USE IN PERFUME COMPOSITIONS FIRMENICH & CIE (CH) 2025-03-12 EP claimed
EP-4416138-A1 NOVEL DERIVATIVES OF GLYCEROL Symrise AG (DE) 2024-08-21 EP claimed
US-20240216246-A1 POWDERY, MUSKY ODORANT MACROCYCLES FIRMENICH & CIE (CH) 2024-07-04 US claimed
WO-2024051975-A1 NOVEL DERIVATIVES OF GLYCEROL SYMRISE AG (DE) 2024-03-14 WO claimed
EP-4048765-B1 POWDERY, MUSKY ODORANT MACROCYCLES FIRMENICH & CIE (CH) 2024-02-28 EP claimed
EP-4312962-A1 POWDERY, MUSKY ODORANT MACROCYCLES Firmenich SA (CH) 2024-02-07 EP claimed
CN-117320686-A Powder incense and musk odorant macrocycle 弗门尼舍有限公司 2023-12-29 CN claimed
US-20230031807-A1 Powdery, Musky Odorant Macrocycles FIRMENICH SA (CH) 2023-02-02 US claimed
WO-2022243300-A1 POWDERY, MUSKY ODORANT MACROCYCLES FIRMENICH SA (CH) 2022-11-24 WO claimed
EP-4048765-A1 POWDERY, MUSKY ODORANT MACROCYCLES Firmenich SA (CH) 2022-08-31 EP claimed
CN-114829560-A Macrocyclic ring with powdery and musk smelling agents 弗门尼舍有限公司 2022-07-29 CN claimed
WO-2021122945-A1 POWDERY, MUSKY ODORANT MACROCYCLES FIRMENICH SA (CH) 2021-06-24 WO claimed
EP-0424787-B1 Use of unsaturated macrocyclic ketones as perfuming ingredients FIRMENICH & CIE (CH) 1996-10-02 EP claimed
US-5266559-A Pentadeceneolide FIRMENICH S.A. (CH) 1993-11-30 US claimed
US-12441954-B2 Powdery, musky odorant macrocycles FIRMENICH SA (CH) 2025-10-14 US disclosed
US-12441954-B2 Powdery, musky odorant macrocycles FIRMENICH SA (CH) 2025-10-14 US disclosed
EP-0424787-B1 Use of unsaturated macrocyclic ketones as perfuming ingredients FIRMENICH & CIE (CH) 1996-10-02 EP disclosed
US-5266559-A Pentadeceneolide FIRMENICH S.A. (CH) 1993-11-30 US disclosed
EP-0424787-A2 Use of unsaturated macrocyclic ketones as perfuming ingredients FIRMENICH SA (CH) 1991-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12441954-B2 Powdery, musky odorant macrocycles OR10J3, MICOS13, MSI2 CA1 4346/4885CA9 4050/4885ALDH1A1 3873/4885
US-20230031807-A1 Powdery, Musky Odorant Macrocycles OR10J3, MICOS13, MSI2 CA1 4346/4885CA9 4050/4885ALDH1A1 3873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.