Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 5/20 | 0.52 |
| ▸ | SYK | P43405 | 7/20 | 0.48 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | ITK | Q08881 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937577 | 0.78 | SYK (0.50) | IGF1RSYKAURKAAURKBPDPK1 | |
| SCHEMBL994027 | 0.76 | SYK (0.45) | SYKEGFRBTK | |
| SCHEMBL3240796 | 0.75 | SYK (0.53) | IGF1RSYKFLT3AURKAAURKB | |
| SCHEMBL2938043 | 0.75 | SYK (0.51) | IGF1RSYKAURKAAURKB | |
| SCHEMBL1937543 | 0.75 | SYK (0.50) | IGF1RSYKAURKAAURKBPDPK1 | |
| SCHEMBL3265649 | 0.74 | AURKA (0.58) | IGF1RSYKFLT3AURKAAURKB | |
| SCHEMBL1934220 | 0.73 | SYK (0.51) | IGF1RSYKFLT3AURKAAURKB | |
| SCHEMBL1934221 | 0.73 | SYK (0.51) | IGF1RSYKFLT3AURKAAURKB | |
| SCHEMBL30819885 | 0.72 | SYK (0.61) | IGF1RSYKFLT3AURKAAURKB | |
| SCHEMBL21795916 | 0.72 | SYK (0.61) | IGF1RSYKFLT3AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115267-A2 | DIAMINOPYRIMIDINES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2009-09-24 | — | — | WO | disclosed |