Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.53 |
| ▸ | IGF1R | P08069 | 8/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | ULK1 | O75385 | 4/20 | 0.44 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.43 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511992 | 0.85 | CTSC (0.52) | SYKULK1ULK2ALK | |
| SCHEMBL2938043 | 0.82 | SYK (0.51) | SYKIGF1RAURKAAURKBULK1 | |
| SCHEMBL1937543 | 0.82 | SYK (0.50) | SYKIGF1RAURKAAURKBULK1 | |
| SCHEMBL1934221 | 0.81 | SYK (0.51) | SYKIGF1RAURKAAURKBFLT3 | |
| SCHEMBL1934220 | 0.81 | SYK (0.51) | SYKIGF1RAURKAAURKBFLT3 | |
| SCHEMBL3264101 | 0.79 | AURKA (0.54) | SYKIGF1RAURKAAURKBULK1 | |
| SCHEMBL1937577 | 0.79 | SYK (0.50) | SYKIGF1RAURKAAURKBULK1 | |
| SCHEMBL15584698 | 0.76 | PAK4 (0.52) | SYKULK1ULK2CDK1FLT3 | |
| SCHEMBL3818817 | 0.75 | IGF1R (0.52) | SYKIGF1RAURKAAURKBFLT3 | |
| SCHEMBL17544410 | 0.74 | SYK (0.50) | SYKIGF1RAURKAAURKBULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025831-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |