Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | CDC25C | P30307 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 9/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652976 | 0.90 | CDC25A (0.46) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL2404462 | 0.86 | CDC25A (0.45) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL2399469 | 0.82 | HSD17B10 (0.43) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL2398451 | 0.78 | CDK4 (0.48) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL2403283 | 0.77 | CDC25A (0.52) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL3546262 | 0.76 | CDC25A (0.46) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL2398380 | 0.74 | CDC25A (0.77) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL2398480 | 0.73 | CDK4 (0.56) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL2401270 | 0.73 | HPGD (0.48) | CDC25ACDC25BCDC25CCDK4MEN1 | |
| SCHEMBL2403315 | 0.72 | CDC25A (0.59) | CDC25ACDC25BCDC25CCDK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831209-B1 | CDC25 PHOSPHATASE INHIBITORS | IPSEN PHARMA (FR) | 2009-08-12 | — | — | EP | claimed |