Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | CDC25C | P30307 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | SPIN4 | Q56A73 | 1/20 | 0.32 |
| ▸ | SPIN3 | Q5JUX0 | 1/20 | 0.32 |
| ▸ | SPIN2B | Q9BPZ2 | 1/20 | 0.32 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.32 |
| ▸ | EIF4E | P06730 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819633 | 0.90 | CDC25A (0.44) | CDC25ACDC25BCDC25CMEN1KMT2A | |
| SCHEMBL3546262 | 0.84 | CDC25A (0.46) | CDC25ACDC25BCDC25CMEN1KMT2A | |
| SCHEMBL2399469 | 0.78 | HSD17B10 (0.43) | CDC25ACDC25BCDC25CMEN1KMT2A | |
| SCHEMBL3548778 | 0.77 | CDC25A (0.60) | CDC25ACDC25BCDC25CMEN1KMT2A | |
| SCHEMBL3553179 | 0.75 | CDC25A (0.51) | CDC25ACDC25BCDC25CMEN1KMT2A | |
| SCHEMBL2404462 | 0.75 | CDC25A (0.45) | CDC25ACDC25BCDC25CMEN1KMT2A | |
| SCHEMBL5311993 | 0.74 | CDC25A (0.61) | CDC25ACDC25BCDC25CMEN1KMT2A | |
| SCHEMBL3549004 | 0.73 | CDC25A (0.57) | CDC25ACDC25BCDC25CMEN1KMT2A | |
| SCHEMBL3543263 | 0.72 | CDC25A (0.52) | CDC25ACDC25BCDC25CKMT2AMALT1 | |
| SCHEMBL3556819 | 0.72 | CDC25A (0.51) | CDC25ACDC25BCDC25CKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814879-B1 | DERIVATIVES OF 4,7-DIOXOBENZOTHIAZOLE-2-CARBOXAMIDES, PREPARATION METHOD THEREOF AND THERAPEUTIC USES OF SAME | SOD CONSEILS RECH APPLIC (FR) | 2008-09-24 | — | — | EP | claimed |