SCHEMBL382

SCHEMBL382

[CH2]C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27856891 0.93
SCHEMBL27403284 0.93
SCHEMBL20595224 0.93
SCHEMBL28226811 0.82
SCHEMBL2575806 0.61
Water SCHEMBL31186927 0.58
Water SCHEMBL1325168 0.58
Water SCHEMBL28491096 0.58
Water SCHEMBL1498163 0.58
Water SCHEMBL28811833 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 31113 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118359624-A Fluoro methyl substituted pyrrolo-indole compound, synthesis method thereof and application thereof in preparation of medicines 河南师范大学 2024-07-19 CN claimed
WO-2024149214-A1 BIFUNCTIONAL COMPOUNDS FOR DEGRADING KRAS-12D VIA UBIQUITIN PROTEASOME PATHWAY NIKANG THERAPEUTICS, INC. (US) 2024-07-18 WO claimed
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118344363-A Tricyclic fused ring derivatives and uses thereof 广东东阳光药业股份有限公司 2024-07-16 CN claimed
CN-113767092-B Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine 劲方医药科技(上海)有限公司 2024-07-16 CN claimed
CN-118324741-A Pyrazole ether compound as well as preparation method and application thereof 南通泰禾化工股份有限公司 2024-07-12 CN claimed
US-20240228499-A1 MASP-2 INHIBITORS AND METHODS OF USE OMEROS CORPORATION (US) 2024-07-11 US claimed
WO-2024148274-A1 COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2024-07-11 WO claimed
EP-3792248-B1 BENZAMIDE COMPOUND AND APPLICATION THEREOF METISA BIOTECHNOLOGY CO LTD (CN) 2024-07-10 EP claimed
EP-4397309-A2 BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF F. Hoffmann-La Roche AG (CH) 2024-07-10 EP claimed
US-3987040-A 3-SUBSTITUTED METHYL-7-ACYLAMINO-7-METHOXY-2-CEPHEM-4-CARBOXYLIC ACID AND ITS ESTERS MERCK & CO., INC. (US) 1976-10-19 US claimed
US-3987168-A INSECTICIDES, ACARICIDES AND NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-10-19 US claimed
US-3975386-A PYRIDOPYRIMIDINE-ONE INTERMEDIATES SANDOZ, INC. (US) 1976-08-17 US claimed
US-3964907-A Method for the preparation of relief printing masters XEROX CORPORATION (US) 1976-06-22 US claimed
US-3953436-A 3,4-Dicarboxycephalosporins and derivatives ELI LILLY AND COMPANY (US) 1976-04-27 US claimed
US-3944545-A Process for preparing desacetoxycephalosporins ELI LILLY AND COMPANY (US) 1976-03-16 US claimed
US-3943098-A 1-Aza-4-thiacyclohexane-4,4-dioxide derivatives and their use as agents protecting against light rays CIBA-GEIGY CORPORATION (US) 1976-03-09 US claimed
US-3936447-A 7-Acylamino-desacetoxy-cephalosporanic acid esters and their production BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed
US-3931215-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed
US-3930671-A Color former and pressure-sensitive copying paper FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed