Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094869 | 0.97 | — | — | |
| SCHEMBL11382364 | 0.72 | — | — | |
| SCHEMBL3815988 | 0.71 | — | — | |
| SCHEMBL10817836 | 0.71 | — | — | |
| SCHEMBL13385702 | 0.69 | — | — | |
| SCHEMBL9530464 | 0.69 | — | — | |
| SCHEMBL7900334 | 0.67 | KDM4E (0.31) | KDM4EALDH1A1MAPT | |
| SCHEMBL416977 | 0.67 | KDM4E (0.31) | KDM4EALDH1A1MAPT | |
| SCHEMBL1456096 | 0.67 | — | — | |
| SCHEMBL3119209 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730148-A4 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | ABBOTT LAB (US) | 2009-08-19 | — | — | EP | claimed |
| EP-1730148-A2 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | Abbott Laboratories (US) | 2006-12-13 | — | — | EP | claimed |
| US-20060025383-A1 | Aminobenzoxazoles as therapeutic agents | ABBOTT LABORATORIES | 2006-02-02 | — | — | US | claimed |
| WO-2005074603-A2 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | ABBOTT LABORATORIES (US) | 2005-08-18 | — | — | WO | claimed |
| EP-0771830-B1 | Curable composition containing cycloolefins, silane and filler | CIBA SC HOLDING AG (CH) | 2003-01-29 | — | — | EP | claimed |
| EP-0844263-B1 | Catalytic mixture for ring-opening metathesis polymerization | CIBA SC HOLDING AG (CH) | 2003-01-15 | — | — | EP | claimed |
| EP-0844264-B1 | Catalytic mixture for ring-opening metathesis polymerization | CIBA SC HOLDING AG (CH) | 2003-01-08 | — | — | EP | claimed |
| EP-0808338-B1 | POLYMERISABLE COMPOSITION, PROCESS FOR PRODUCING CROSS-LINKED POLYMERS, AND CROSS-LINKABLE POLYMERS | CIBA SC HOLDING AG (CH) | 1999-11-17 | — | — | EP | claimed |
| EP-0807137-B1 | POLYMERISABLE COMPOSITION, PROCESS FOR PRODUCING CROSS-LINKED POLYMERS, AND CROSS-LINKABLE POLYMERS | CIBA GEIGY AG (CH) | 1999-08-04 | — | — | EP | claimed |
| EP-2826778-B1 | Azaindole derivatives as CFTR modulators | VERTEX PHARMA (US) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016034262-A1 | FORMULATIONS AND ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-03-10 | — | — | WO | disclosed |
| WO-2014094962-A2 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
| US-7696291-B2 | Fluoropolymer for chromatic aberration-free lens and chromatic aberration-free lens | ASAHI GLASS COMPANY, LIMITED (JP) | 2010-04-13 | — | — | US | disclosed |
| EP-1730148-A4 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | ABBOTT LAB (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-1730148-A2 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | Abbott Laboratories (US) | 2006-12-13 | — | — | EP | disclosed |
| US-20060025383-A1 | Aminobenzoxazoles as therapeutic agents | ABBOTT LABORATORIES | 2006-02-02 | — | — | US | disclosed |
| WO-2005074603-A2 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | ABBOTT LABORATORIES (US) | 2005-08-18 | — | — | WO | disclosed |
| US-4582905-A | CHEMICAL INTERMEDIATES FOR 3-SUBSTITUTED -2-==HYDROXYPROPYLARYL ETHER BETA-BLOCKERS | SHIONOGI & CO., LTD. (JP) | 1986-04-15 | — | — | US | disclosed |
| US-4582905-A | CHEMICAL INTERMEDIATES FOR 3-SUBSTITUTED -2-==HYDROXYPROPYLARYL ETHER BETA-BLOCKERS | SHIONOGI & CO., LTD. (JP) | 1986-04-15 | — | — | US | disclosed |
| US-4506079-A | AROMATIZATION HYPOTENSIVE AGENTS, VASODILATION | SHIONOGI & CO., LTD. (JP) | 1985-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025383-A1 | Aminobenzoxazoles as therapeutic agents | ABL1, MAP3K19, MAP3K20 | KDM4E 403/4885ALDH1A1 1952/4885MAPT 2567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.