Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822819 | 0.89 | GCGR (0.43) | MAPTGCGRALDH1A1KDM4EHPGD | |
| SCHEMBL9753340 | 0.89 | GCGR (0.43) | MAPTGCGRALDH1A1KDM4EHPGD | |
| SCHEMBL5089841 | 0.89 | GCGR (0.43) | MAPTGCGRALDH1A1KDM4EHPGD | |
| SCHEMBL5094505 | 0.89 | GCGR (0.47) | MAPTGCGRALDH1A1KDM4EHPGD | |
| SCHEMBL5095559 | 0.89 | GCGR (0.43) | MAPTGCGRALDH1A1KDM4EHPGD | |
| SCHEMBL5095533 | 0.88 | GCGR (0.42) | MAPTGCGRALDH1A1KDM4EHPGD | |
| SCHEMBL5093104 | 0.88 | MAPT (0.44) | MAPTGCGRALDH1A1KDM4EHPGD | |
| SCHEMBL3819543 | 0.88 | GCGR (0.42) | MAPTGCGRALDH1A1KDM4EHPGD | |
| SCHEMBL5101498 | 0.88 | ALDH1A1 (0.44) | MAPTGCGRALDH1A1KDM4EHPGD | |
| SCHEMBL3822321 | 0.87 | GCGR (0.41) | MAPTGCGRALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581535-B3 | PYRROLOPYRIDAZINE DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2009-09-02 | — | — | EP | claimed |