Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 14/20 | 0.37 |
| ▸ | PLAU | P00749 | 3/20 | 0.36 |
| ▸ | F9 | P00740 | 3/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.34 |
| ▸ | SELE | P16581 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821498 | 0.90 | SLC9A1 (0.38) | SLC9A1PLAUF9F10 | |
| SCHEMBL3818309 | 0.88 | SLC9A1 (0.36) | SLC9A1PLAUF9F10 | |
| SCHEMBL3813765 | 0.86 | PLAU (0.54) | SLC9A1PLAUF9F10 | |
| SCHEMBL3817293 | 0.85 | SLC9A1 (0.37) | SLC9A1PLAUF9F10 | |
| SCHEMBL3815869 | 0.83 | SLC9A1 (0.52) | SLC9A1PLAUF9F10 | |
| SCHEMBL3814870 | 0.81 | SLC9A1 (0.47) | SLC9A1PLAUF9 | |
| SCHEMBL3818017 | 0.80 | SLC9A1 (0.55) | SLC9A1PLAUF9F10 | |
| SCHEMBL3817053 | 0.80 | PRP4K (0.39) | SLC9A1PLAUF9F10 | |
| SCHEMBL3814353 | 0.80 | SLC9A1 (0.51) | SLC9A1PLAUF9F10 | |
| SCHEMBL3815060 | 0.80 | SLC9A1 (0.56) | SLC9A1PLAUF9F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831192-A4 | BENZOTHIOPHEN-2-CARBONYLGUANIDINE DERIVATIVES, PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RES INST CHEM TECH (KR) | 2009-08-19 | — | — | EP | disclosed |
| EP-1831192-A1 | BENZOTHIOPHEN-2-CARBONYLGUANIDINE DERIVATIVES, PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Korea Research Institute of Chemical Technology (KR) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006071047-A1 | BENZOTHIOPHEN-2-CARBONYLGUANIDINE DERIVATIVES, PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-07-06 | — | — | WO | disclosed |