Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17086736 | 1.00 | SLC6A3 (0.50) | SLC6A3HPGDGAATDP1L3MBTL1 | |
| SCHEMBL17113744 | 1.00 | SLC6A3 (0.50) | SLC6A3HPGDGAATDP1L3MBTL1 | |
| SCHEMBL12846895 | 1.00 | SLC6A3 (0.50) | SLC6A3HPGDGAATDP1L3MBTL1 | |
| SCHEMBL17086735 | 1.00 | SLC6A3 (0.50) | SLC6A3HPGDGAATDP1L3MBTL1 | |
| SCHEMBL17086732 | 1.00 | SLC6A3 (0.50) | SLC6A3HPGDGAATDP1L3MBTL1 | |
| SCHEMBL19493796 | 0.95 | SLC6A3 (0.56) | SLC6A3HPGDGAATDP1L3MBTL1 | |
| SCHEMBL12788159 | 0.82 | SLC6A3 (0.48) | SLC6A3HPGDGAATDP1L3MBTL1 | |
| SCHEMBL17084110 | 0.82 | SLC6A3 (0.48) | SLC6A3HPGDGAATDP1L3MBTL1 | |
| SCHEMBL17084116 | 0.82 | SLC6A3 (0.48) | SLC6A3HPGDGAATDP1L3MBTL1 | |
| SCHEMBL17084107 | 0.82 | SLC6A3 (0.48) | SLC6A3HPGDGAATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622240-B | Fused Substituted Aminopyrrolidine Derivatives | DAIICHI SANKYO CO LTD | 2014-07-23 | — | — | CN | disclosed |
| CN-101622240-A | Fused Substituted Aminopyrrolidine Derivatives | DAIICHI SANKYO CO LTD | 2010-01-06 | — | — | CN | disclosed |
| EP-2097400-A2 | FUSED SUBSTITUTED AMINOPYRROLIDINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008082009-A2 | FUSED SUBSTITUTED AMINOPYRROLIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-07-10 | — | — | WO | disclosed |