Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813536 | 0.96 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3PTPN7KCNH2 | |
| SCHEMBL3817587 | 0.81 | ALDH1A1 (0.44) | SLC6A4SLC6A2KCNH2CYP2D6HPGD | |
| SCHEMBL3816738 | 0.77 | ALDH1A1 (0.46) | SLC6A4SLC6A2SLC6A3HPGDHTT | |
| SCHEMBL3812235 | 0.74 | SLC6A2 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3821621 | 0.71 | ALDH1A1 (0.41) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3813701 | 0.71 | KDM4E (0.41) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL1305319 | 0.70 | HPGD (0.44) | PTPN7HPGDHTTRAB9A | |
| SCHEMBL1305316 | 0.70 | HPGD (0.44) | PTPN7HPGDHTTRAB9A | |
| SCHEMBL3811762 | 0.68 | ALDH1A1 (0.43) | SLC6A4SLC6A2SLC6A3HPGDHTT | |
| SCHEMBL1306649 | 0.67 | HPGD (0.46) | PTPN7HPGDHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089354-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008054154-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |