Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 16/20 | 0.49 |
| ▸ | RARA | P10276 | 14/20 | 0.49 |
| ▸ | RARG | P13631 | 14/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382277 | 0.83 | RARA (0.66) | RARBRARARARG | |
| SCHEMBL383525 | 0.81 | RARG (0.62) | RARBRARARARGPGR | |
| SCHEMBL380874 | 0.80 | RARA (0.51) | RARBRARARARGPGR | |
| SCHEMBL4576607 | 0.79 | RARB (0.60) | RARBRARARARG | |
| SCHEMBL382090 | 0.77 | RARA (0.48) | RARBRARARARGPGR | |
| SCHEMBL382210 | 0.75 | RARB (0.57) | RARBRARARARG | |
| SCHEMBL382630 | 0.75 | RARG (0.79) | RARBRARARARGCYP4F2CYP4A11 | |
| SCHEMBL381907 | 0.74 | RARA (0.66) | RARBRARARARG | |
| SCHEMBL381583 | 0.74 | RARA (0.68) | RARBRARARARG | |
| SCHEMBL381777 | 0.73 | RARA (0.55) | RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | disclosed |