Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Thiazolidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiazolidine SCHEMBL7107836 | 1.00 | — | — | |
| Thiazolidine SCHEMBL10754857 | 0.90 | — | — | |
| Thiazolidine SCHEMBL3347398 | 0.90 | — | — | |
| Thiazolidine SCHEMBL16058281 | 0.90 | — | — | |
| Fumaric Acid SCHEMBL1694365 | 0.85 | TSHR (0.41) | — | |
| Fumaric Acid SCHEMBL4951314 | 0.85 | TSHR (0.41) | — | |
| Pyruvate SCHEMBL14335413 | 0.85 | — | — | |
| Thiazolidine SCHEMBL7360 | 0.85 | — | — | |
| Thiazolidine SCHEMBL131493 | 0.85 | — | — | |
| Thiazolidine SCHEMBL5484388 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3727314-B1 | DEODORANT COMPOSITIONS | UNILEVER IP HOLDINGS B V (NL) | 2021-10-13 | — | — | EP | claimed |
| EP-2830666-B1 | EFFICIENT SYNTHESIS OF ETHYLENEDICYSTEINE-SUGAR CONJUGATES FOR IMAGING AND THERAPY | UNIV TEXAS (US) | 2020-01-08 | — | — | EP | claimed |
| EP-1087991-B1 | PRODRUGS OF DIPEPTIDYL PEPTIDASE IV INHIBITORS | PROSIDION LTD (GB) | 2009-09-02 | — | — | EP | claimed |
| EP-1624897-B1 | HIV PRODRUGS CLEAVABLE BY CD26 | TIBOTEC PHARM LTD (IE) | 2007-10-10 | — | — | EP | claimed |
| EP-0922051-B1 | PROCESS FOR THE PRODUCTION OF SALTS OF ERYTHROMYCIN, ROXITHROMYCIN, CLARITHROMYCIN AND AZITHROMYCIN | RUSSINSKY LTD (IE) | 2001-05-09 | — | — | EP | claimed |
| EP-1090030-A1 | COMPOUNDS OF UNSTABLE DIPEPTIDYL PEPTIDASE IV INHIBITORS | Probiodrug Gesellschaft für Arzneimittelforschung mbH (DE) | 2001-04-11 | — | — | EP | claimed |
| EP-1087991-A1 | PRODRUGS OF DIPEPTIDYL PEPTIDASE IV INHIBITORS | Probiodrug Gesellschaft für Arzneimittelforschung mbH (DE) | 2001-04-04 | — | — | EP | claimed |
| WO-1999067278-A1 | PRODRUGS OF DIPEPTIDYL PEPTIDASE IV INHIBITORS | Probiodrug Gesellschaft für Arzneimittelforschung mbH (DE) | 1999-12-29 | — | — | WO | claimed |
| WO-1999067279-A1 | COMPOUNDS OF UNSTABLE DIPEPTIDYL PEPTIDASE IV INHIBITORS | Probiodrug Gesellschaft für Arzneimittelforschung mbH (DE) | 1999-12-29 | — | — | WO | claimed |
| EP-0408106-B1 | Novel acrylic amide derivatives, a process for their preparation, pharmaceutical compositions containing the same and their use in medicine | RICHTER GEDEON VEGYESZET (HU) | 1994-04-06 | — | — | EP | claimed |
| EP-0518323-A1 | Method for production of a radiographic recording material with reduced sensitivity to light | DU PONT DE NEMOURS (DEUTSCHLAND) GMBH (DE) | 1992-12-16 | — | — | EP | claimed |
| EP-0187956-A2 | Pharmaceutical composition for the treatment of defects of the gastrointestinal mucous membrane | BOEHRINGER INGELHEIM KG (DE) | 1986-07-23 | — | — | EP | claimed |
| EP-0009898-B1 | NOVEL ANTI-HYPERTENSIVE MERCAPTOACYLAMINO ACID DERIVATIVES, THEIR PREPARATION AND USE | UNIVERSITY OF MIAMI (US) | 1983-05-18 | — | — | EP | claimed |
| EP-1087991-B1 | PRODRUGS OF DIPEPTIDYL PEPTIDASE IV INHIBITORS | PROSIDION LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008049401-A2 | NAIL VARNISH FOR COSMETIC AND MEDICAL APPLICATIONS | SUSILO RUDY (DE) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008049402-A2 | NAIL VARNISH REMOVER FOR COSMETIC AND MEDICAL APPLICATIONS | SUSILO RUDY (DE) | 2008-05-02 | — | — | WO | disclosed |
| US-4304785-A | LIVER PROTECTIVE AGENTS | PLC PHARMACEUTICAL LICENCES COMPANY LIMITED (CH) | 1981-12-08 | — | — | US | disclosed |
| US-4256764-A | LIVER DISORDERS; WATER SOLUBILITY; REACTION WITH AN OXAZOLIDINE | PLC PHARMACEUTICAL LICENSES CO. LTD. (CH) | 1981-03-17 | — | — | US | disclosed |
| EP-0011598-A1 | Process for the preparation of derivatives of isoeugenol dimers | PLC PHARMACEUTICAL LICENCES COMPANY LTD. (CH) | 1980-05-28 | — | — | EP | disclosed |
| EP-0004522-A2 | New compounds related to dilignols, compounds related to dilignols for use in the treatment of liver deseases and pharmaceutical compositions containing them | PHARMACEUTICAL LICENCES COMPANY LTD. (CH) | 1979-10-03 | — | — | EP | disclosed |