Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 6/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GLB1 | P16278 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28802088 | 0.91 | BCHE (0.51) | EPHX1EPHX2BCHEL3MBTL1ALDH1A1 | |
| SCHEMBL13207267 | 0.87 | EPHX1 (0.49) | EPHX1EPHX2BCHEGNAI3GNAO1 | |
| SCHEMBL16511590 | 0.87 | EPHX1 (0.49) | EPHX1EPHX2BCHEGNAI3GNAO1 | |
| SCHEMBL1920273 | 0.85 | HRH2 (0.40) | EPHX1EPHX2HTR1ADRD2DRD4 | |
| SCHEMBL26619861 | 0.84 | ADRA1D (0.38) | HTR1ADRD2DRD4LTA4HHTR7 | |
| SCHEMBL13738688 | 0.83 | EPHX1 (0.44) | EPHX1EPHX2DRD2DRD4L3MBTL1 | |
| SCHEMBL13738686 | 0.83 | EPHX1 (0.44) | EPHX1EPHX2DRD2DRD4L3MBTL1 | |
| SCHEMBL13739085 | 0.83 | EPHX1 (0.44) | EPHX1EPHX2DRD2DRD4L3MBTL1 | |
| SCHEMBL25094726 | 0.83 | BCHE (0.49) | EPHX1EPHX2BCHEGNAI3GNAO1 | |
| SCHEMBL1920984 | 0.81 | MC4R (0.44) | HTR1ADRD2DRD4LTA4HKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365996-A | Imidazopyridine derivative compounds and uses thereof | 韩美药品株式会社 | 2021-09-07 | — | — | CN | disclosed |
| EP-2089354-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008054154-A1 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |