Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.83 |
| ▸ | TP53 | P04637 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13053140 | 0.86 | SMN1; SMN2 (0.89) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL4650036 | 0.86 | TP53 (0.89) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL4688937 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL1906381 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL31265500 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL4829133 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL31265474 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL10849069 | 0.83 | TP53 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL1906504 | 0.83 | TP53 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL1420033 | 0.82 | TP53 (0.81) | SMN1; SMN2TP53LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812455-A | Benzoxazoles Process for the preparation of compounds | 中国海洋石油集团有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-117836291-A | Cyano-substituted carbazole derivative and organic electroluminescent device comprising same | 株式会社乐普拓 | 2024-04-05 | — | — | CN | disclosed |
| CN-117836293-A | Tertiary amine derivative and organic electroluminescent device comprising same | 株式会社乐普拓 | 2024-04-05 | — | — | CN | disclosed |
| EP-1730148-A4 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | ABBOTT LAB (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-1730148-A2 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | Abbott Laboratories (US) | 2006-12-13 | — | — | EP | disclosed |
| US-20060025383-A1 | Aminobenzoxazoles as therapeutic agents | ABBOTT LABORATORIES | 2006-02-02 | — | — | US | disclosed |
| WO-2005074603-A2 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | ABBOTT LABORATORIES (US) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025383-A1 | Aminobenzoxazoles as therapeutic agents | ABL1, MAP3K19, MAP3K20 | SMN1; SMN2 4325/4885TP53 2697/4885LMNA 3823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.