Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.83 |
| ▸ | TP53 | P04637 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | NPC1 | O15118 | 6/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | GFER | P55789 | 1/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | GRK6 | P43250 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13053140 | 0.86 | SMN1; SMN2 (0.89) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL4650036 | 0.86 | TP53 (0.89) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL31265474 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL1906381 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL10849069 | 0.83 | TP53 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL31265500 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL4688937 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL1906504 | 0.83 | TP53 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL3821992 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2TP53LMNANPC1RAB9A | |
| SCHEMBL1420033 | 0.82 | TP53 (0.81) | SMN1; SMN2TP53LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287438-A1 | Agent for preventing or treating neuropathy | MOMOSE YU | 2008-11-20 | — | — | US | disclosed |
| US-7423159-B2 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-09 | — | — | US | disclosed |
| US-20060004069-A1 | Agent for preventing or treating neuropathy | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-05 | — | — | US | disclosed |
| CN-1026322-C | Process for preparing benzodumb azole derivatives | TANABE SEIYAKU CO (JP) | 1994-10-26 | — | — | CN | disclosed |
| CN-88101542-A | Benzoxazole derivatives and process for preparing them | — | 1988-10-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004069-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | SMN1; SMN2 75/4885TP53 4623/4885LMNA 2405/4885 |
| US-20080287438-A1 | Agent for preventing or treating neuropathy | NR2C2, NR0B2, NR2E1 | SMN1; SMN2 75/4885TP53 4623/4885LMNA 2405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.