Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2700735 | 0.83 | TDP1 (0.65) | TDP1SMN1; SMN2HRH3PDK1MEN1 | |
| SCHEMBL28659846 | 0.77 | TDP1 (0.71) | TDP1SMN1; SMN2HRH3PDK1MEN1 | |
| SCHEMBL3250460 | 0.77 | TDP1 (0.71) | TDP1SMN1; SMN2HRH3PDK1MEN1 | |
| SCHEMBL3260505 | 0.74 | SLC6A2 (0.45) | SMN1; SMN2GRM2 | |
| Ammonia Solution, Strong SCHEMBL27469604 | 0.72 | SLC6A2 (0.44) | SMN1; SMN2GRM2 | |
| SCHEMBL1582872 | 0.72 | TDP1 (1.00) | TDP1SMN1; SMN2HRH3PDK1MEN1 | |
| SCHEMBL31220 | 0.72 | TDP1 (1.00) | TDP1SMN1; SMN2HRH3PDK1MEN1 | |
| SCHEMBL1583161 | 0.72 | TDP1 (1.00) | TDP1SMN1; SMN2HRH3PDK1MEN1 | |
| SCHEMBL17028904 | 0.72 | TDP1 (1.00) | TDP1SMN1; SMN2HRH3PDK1MEN1 | |
| Oxirane SCHEMBL1004512 | 0.72 | TDP1 (0.89) | TDP1SMN1; SMN2HRH3PDK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828127-A4 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-äÝ4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL¨-(4-PIPERIDYL)üMETHANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-04-29 | — | — | EP | disclosed |
| US-20090082203-A1 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-{[4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL]- (4-PIPERIDYL)}METHANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-03-26 | — | — | US | disclosed |
| EP-1828127-A2 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-äÝ4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL¨-(4-PIPERIDYL)üMETHANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006065659-A2 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-{[4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL]-(4-PIPERIDYL)}METHANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082203-A1 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-{[4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL]- (4-PIPERIDYL)}METHANE DERIVATIVES | DDT, API5, MSL1 | TDP1 3184/4885SMN1; SMN2 768/4885HRH3 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.