SCHEMBL382223

SCHEMBL382223

CC(=O)CC(=O)Nc1ccccc1C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.67
HPGD P15428 7/20 0.66
ALOX12 P18054 1/20 0.66
ALDH1A1 P00352 4/20 0.66
SMN1; SMN2 Q16637 1/20 0.65
NPC1 O15118 2/20 0.62
MAPT P10636 2/20 0.60
MAPK1 P28482 2/20 0.60
LMNA P02545 2/20 0.60
HDAC3 O15379 1/20 0.60
HDAC4 P56524 1/20 0.60
HDAC1 Q13547 1/20 0.60
HDAC7 Q8WUI4 1/20 0.60
HDAC2 Q92769 1/20 0.60
HDAC10 Q969S8 1/20 0.60
HDAC11 Q96DB2 1/20 0.60
HDAC8 Q9BY41 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
HDAC9 Q9UKV0 1/20 0.60
HDAC5 Q9UQL6 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30065998 1.00 RAB9A (0.67) RAB9AHPGDALOX12ALDH1A1SMN1; SMN2
SCHEMBL29528561 0.90 RAB9A (0.73) RAB9AHPGDALOX12ALDH1A1SMN1; SMN2
SCHEMBL2005846 0.90 RAB9A (0.73) RAB9AHPGDALOX12ALDH1A1SMN1; SMN2
SCHEMBL2912340 0.88 MAPT (0.58) RAB9AHPGDALOX12ALDH1A1SMN1; SMN2
SCHEMBL31365405 0.85 HDAC3 (0.62) RAB9AHPGDALDH1A1NPC1MAPT
SCHEMBL7078969 0.85 HDAC3 (0.62) RAB9AHPGDALDH1A1NPC1MAPT
SCHEMBL7284784 0.85 HPGD (0.66) RAB9AHPGDALOX12ALDH1A1SMN1; SMN2
SCHEMBL11182704 0.85 RAB9A (0.72) RAB9AHPGDALOX12ALDH1A1SMN1; SMN2
SCHEMBL29389339 0.85 RAB9A (0.72) RAB9AHPGDALOX12ALDH1A1SMN1; SMN2
SCHEMBL29575287 0.85 HPGD (0.66) RAB9AHPGDALOX12ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 544 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118909458-A 3D acid modified biphenyl amine organic pigment, and preparation method and application thereof 瑞安宝源化工有限公司 2024-11-08 CN claimed
CN-115449498-A Stenotrophomonas, microbial inoculum, method for degrading aromatic amine wastewater by using stenotrophomonas and microbial inoculum and treatment system 江苏聚庚科技股份有限公司 2022-12-09 CN claimed
WO-2022228846-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-11-03 WO claimed
WO-2022117389-A1 METHOD FOR PRODUCING A TERMINAL-FUNCTIONAL POLYMER BASF SE (DE) 2022-06-09 WO claimed
CN-113717546-A Method for preparing organic pigment yellow and pigment orange by modifying attapulgite 宇虹颜料股份有限公司 2021-11-30 CN claimed
CN-211310016-U Material delivery and transfer device used before packaging of o-methylacetanilide 盐城华钛化学有限公司 2020-08-21 CN claimed
CN-108559298-B Application of multi-block copolymer containing PPO-PEO and PDMS in preparation of modified organic pigment 百合花集团股份有限公司 2019-12-06 CN claimed
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 EP claimed
US-8507625-B2 Michael acceptor having multiple hydroxyl groups, and Michael addition product derived therefrom KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2013-08-13 US claimed
EP-1545876-B1 LIQUID UNCROSSLINKED MICHAEL ADDITION OLIGOMERS PREPARED IN THE PRESENCE OF A CATALYST HAVING BOTH AN EPOXY MOIETY AND A QUATERNARY SALT ASHLAND LICENSING & INTELLECTU (US) 2012-05-09 EP claimed
EP-0105080-B1 A METHOD FOR ALKOXYLATION VISTA CHEMICAL COMPANY (US) 1987-07-01 EP claimed
US-4643770-A TETRAZOTIZED 3,3'-DICHLOROBENZIDINE REACTED WITH ACETOACETARYLIDIDE AND KETIMINE BASF CORPORATION, INMONT DIVISION (US) 1987-02-17 US claimed
US-4602960-A Modified diarylide pigments and their preparation BASF FARBEN & FASERN AKTIENGESELLSCHAFT (DE) 1986-07-29 US claimed
EP-0105080-A2 A method for alkoxylation VISTA CHEMICAL COMPANY (US) 1984-04-11 EP claimed
EP-0104309-A2 Catalysts for alkoxylation reactions VISTA CHEMICAL COMPANY (US) 1984-04-04 EP claimed
US-4376868-A Alkoxylation of cresylic acids CONOCO INC. (US) 1983-03-15 US claimed
EP-0049358-A1 Strontium and barium containing alkoxylation systems for unsaturated alcohols Conoco Phillips Company (US) 1982-04-14 EP claimed
EP-0046947-A1 Strontium and barium containing alkoxylation systems Conoco Phillips Company (US) 1982-03-10 EP claimed
US-4204871-A Printing inks containing nucleated organic pigments SUN CHEMICAL CORPORATION (US) 1980-05-27 US claimed
US-4111703-A HEAT-SENSITIVE COATING COMPOSITION WITH 4-AROMATIC AND HYDROXY SUBSTITUTED PIPERIDINE DERIVATIVE AND CYCLIC POLYKETO COMPOUND GRAPHIC CONTROLS CORPORATION (US) 1978-09-05 US claimed