Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 9/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11790689 | 0.85 | MCHR1 (0.52) | MCHR1CNR2TAS2R14POLBNR3C1 | |
| SCHEMBL28508064 | 0.83 | MCHR1 (0.54) | MCHR1CNR2TAS2R14POLBNR3C1 | |
| SCHEMBL11661989 | 0.76 | CNR2 (0.56) | MCHR1CNR2ALDH1A1ACHEBCHE | |
| SCHEMBL6315850 | 0.75 | CA12 (0.56) | MCHR1CNR2NR3C1ALDH1A1LMNA | |
| SCHEMBL6872283 | 0.75 | MCHR1 (0.58) | MCHR1CNR2TAS2R14POLBNR3C1 | |
| SCHEMBL10719271 | 0.74 | MCHR1 (0.67) | MCHR1CNR2TAS2R14POLBNR3C1 | |
| SCHEMBL2890 | 0.73 | CA9 (0.53) | MCHR1CNR2ALDH1A1LMNAACHE | |
| SCHEMBL11785484 | 0.73 | PPARG (0.43) | TAS2R14POLBALDH1A1LMNACA12 | |
| SCHEMBL21835092 | 0.73 | CNR2 (0.65) | MCHR1CNR2TAS2R14NR3C1ALDH1A1 | |
| SCHEMBL5530229 | 0.73 | MCHR1 (0.56) | MCHR1CNR2TAS2R14POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097370-A2 | COMPOUNDS AND METHODS FOR AMINO-ALKYLENEDIOL SYNTHESIS | F. Hoffmann-Roche AG (CH) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008077799-A2 | COMPOUNDS AND METHODS FOR AMINO-ALKYLENEDIOL SYNTHESIS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-07-03 | — | — | WO | disclosed |
| US-20080154063-A1 | Compounds and methods for amino-alkylenediol synthesis | ROCHE PALO ALTO LLC | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154063-A1 | Compounds and methods for amino-alkylenediol synthesis | DAO, MSMO1, STS | MCHR1 3040/4885CNR2 1723/4885TAS2R14 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.