Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 8/20 | 0.54 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.52 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15826671 | 0.90 | TSHR (0.63) | TSHRALDH1A1CNR2CA12CA9 | |
| SCHEMBL10719271 | 0.89 | MCHR1 (0.67) | MCHR1TSHRALDH1A1CNR2TAS2R14 | |
| SCHEMBL11614386 | 0.84 | MCHR1 (0.61) | MCHR1ALDH1A1CNR2TAS2R14CNR1 | |
| SCHEMBL10544587 | 0.84 | TAAR1 (0.58) | MCHR1ALDH1A1CNR2CYP1A2CYP2C19 | |
| SCHEMBL8143415 | 0.84 | MCHR1 (0.56) | MCHR1TSHRALDH1A1CNR2TAS2R14 | |
| SCHEMBL5743796 | 0.84 | CNR2 (0.50) | MCHR1CNR2TAS2R14LIMK2CNR1 | |
| Diphenylmethane SCHEMBL9099741 | 0.83 | SMN1; SMN2 (0.54) | MCHR1TSHRALDH1A1CNR2TAS2R14 | |
| Sulfuric Acid SCHEMBL6574025 | 0.82 | ALDH1A1 (0.74) | TSHRALDH1A1CA12CYP3A4CA9 | |
| Sulfuric Acid SCHEMBL6574021 | 0.82 | ALDH1A1 (0.74) | TSHRALDH1A1CA12CYP3A4CA9 | |
| SCHEMBL5744364 | 0.82 | SIGMAR1 (0.51) | MCHR1CNR2TAS2R14ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244504-B2 | Phenol-free decorative laminates and method of producing the same | ACKNER FRITZ | 2007-07-17 | — | — | US | disclosed |
| US-7235303-B2 | Phenol-free decorative laminates and method of producing the same | DAKOR MELAMIN IMPRAGNIERUNGEN GMBH (DE) | 2007-06-26 | — | — | US | disclosed |
| US-20060228572-A1 | Phenol-free decorative laminates and method of producing the same | DAKOR MELAMIN IMPRAGNIERUNGEN GMBH (DE) | 2006-10-12 | — | — | US | disclosed |
| US-20060182986-A1 | Phenol-free decorative laminates and method of producing the same | ACKNER FRITZ | 2006-08-17 | — | — | US | disclosed |
| EP-1391478-A1 | Phenol-free decorative laminate and method of producing same | Cassaghi, Pietro (IT) | 2004-02-25 | — | — | EP | disclosed |