SCHEMBL3823183

SCHEMBL3823183

CCCCCC(CC)/C(C(=O)O)=C(/C(=O)O)C(CC)CCCCC

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.59
MAPK1 P28482 1/20 0.59
CA1 P00915 4/20 0.52
GRIK1 P39086 2/20 0.48
GRIK2 Q13002 2/20 0.48
SLC1A2 P43004 1/20 0.48
SLC1A1 P43005 1/20 0.48
GPR84 Q9NQS5 6/20 0.47
FFAR1 O14842 1/20 0.47
MAPT P10636 1/20 0.45
LCK P06239 1/20 0.45
PPARD Q03181 1/20 0.45
ZDHHC20 Q5W0Z9 1/20 0.45
ZDHHC2 Q9UIJ5 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3823186 1.00 CA2 (0.59) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL19435808 0.98 CA2 (0.57) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL19435811 0.98 CA2 (0.57) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL342624 0.87 CA2 (0.50) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL5611696 0.85 CA2 (0.48) CA2MAPK1CA1GRIK1GRIK2
Oxalic Acid SCHEMBL28551222 0.83 CA2 (0.79) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL23829870 0.82 CA2 (0.86) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL8606737 0.82 CA2 (0.86) CA2MAPK1CA1GRIK1GRIK2
SCHEMBL29946 0.82 CA2 (0.86) CA2MAPK1CA1GRIK1GRIK2
Oxalic Acid SCHEMBL17714532 0.81 CA2 (0.76) CA2MAPK1CA1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1368057-B1 METHOD TO ENHANCE THE IMMUNOGENICITY OF AN ANTIGEN TORREY PINES INST (US) 2009-08-26 EP disclosed
US-7229621-B2 Method to enhance the immunogenicity of an antigen TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 2007-06-12 US disclosed
EP-1071411-B1 TOPICAL IMMUNOSTIMULATION TO INDUCE LANGERHANS CELL MIGRATION TORREY PINES INST (US) 2007-03-14 EP disclosed
EP-1071411-A4 TOPICAL IMMUNOSTIMULATION TO INDUCE LANGERHANS CELL MIGRATION TORREY PINES INST (US) 2004-12-08 EP disclosed
EP-1368057-A2 METHOD TO ENHANCE THE IMMUNOGENICITY OF AN ANTIGEN Lancell, Llc (US) 2003-12-10 EP disclosed
WO-2002074332-A2 METHOD TO ENHANCE THE IMMUNOGENICITY OF AN ANTIGEN LANCELL, LLC (US) 2002-09-26 WO disclosed
US-6210672-B1 TOPICAL ADMINISTRATION OF AN ANTIGEN OR A PORTION THEREOF IN CONJUNCTION WITH AN ENHANCER OF SKIN PENETRATION AND AN INDUCER OF LANGERHANS CELL MIGRATION. TORREY PINES INSTITUTE FOR MOLECULAR STUDIES 2001-04-03 US disclosed
EP-1071411-A1 TOPICAL IMMUNOSTIMULATION TO INDUCE LANGERHANS CELL MIGRATION TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 2001-01-31 EP disclosed
WO-1999053912-A1 TOPICAL IMMUNOSTIMULATION TO INDUCE LANGERHANS CELL MIGRATION TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1999-10-28 WO disclosed