Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.78 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.78 |
| ▸ | ITGAV | P06756 | 18/20 | 0.78 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383385 | 0.94 | ITGB3 (0.79) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL6496727 | 0.94 | ITGB3 (0.76) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL382591 | 0.94 | ITGB3 (0.81) | ITGB3ITGA2BITGAV | |
| SCHEMBL7465516 | 0.92 | ITGB3 (0.79) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL382753 | 0.88 | ITGB3 (1.00) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL30856557 | 0.88 | ITGB3 (1.00) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL7465504 | 0.87 | ITGB3 (0.62) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL6497468 | 0.86 | ITGB3 (0.79) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL6499233 | 0.86 | ITGB3 (0.89) | ITGB3ITGA2BITGAVITGB1ITGB5 | |
| SCHEMBL382334 | 0.86 | ITGB3 (0.60) | ITGB3ITGA2BITGAVITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | claimed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | claimed |
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |