Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GPR6 | P46095 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514186 | 0.91 | SLC6A9 (0.63) | SLC6A9ATMRAB9AKMT2ANPC1 | |
| SCHEMBL515419 | 0.83 | SLC6A9 (0.53) | SLC6A9ATMRAB9AKMT2ANPC1 | |
| SCHEMBL2605270 | 0.82 | SLC6A9 (0.64) | SLC6A9ATMRAB9AKMT2ANPC1 | |
| SCHEMBL514551 | 0.81 | SLC6A9 (0.52) | SLC6A9ATMRAB9AKMT2ANPC1 | |
| SCHEMBL787486 | 0.79 | SLC6A9 (0.65) | SLC6A9HPGD | |
| SCHEMBL787020 | 0.77 | SLC6A9 (0.58) | SLC6A9KMT2AMEN1HPGD | |
| SCHEMBL787450 | 0.76 | SLC6A9 (0.74) | SLC6A9 | |
| SCHEMBL4182935 | 0.76 | SLC6A9 (0.61) | SLC6A9ATMRAB9AKMT2ANPC1 | |
| SCHEMBL7894785 | 0.76 | SLC6A9 (1.00) | SLC6A9 | |
| SCHEMBL3704810 | 0.76 | SLC6A9 (1.00) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408763-A2 | DERIVATIVES OF N-Ý(2-AZA-BICYCLOÝ2.1.1¨HEX-1-YL)-ARYL-METHYL¨-HETEROBENZAMIDE, PREPARATION THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI (FR) | 2012-01-25 | — | — | EP | claimed |
| WO-2010106269-A2 | DERIVATIVES OF N-[(2-AZA-BICYCLO[2.1.1]HEX-1-YL)-ARYL-METHYL]-HETEROBENZAMIDE, PREPARATION THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2010-09-23 | — | — | WO | claimed |
| EP-2408763-A2 | DERIVATIVES OF N-Ý(2-AZA-BICYCLOÝ2.1.1¨HEX-1-YL)-ARYL-METHYL¨-HETEROBENZAMIDE, PREPARATION THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI (FR) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010106269-A2 | DERIVATIVES OF N-[(2-AZA-BICYCLO[2.1.1]HEX-1-YL)-ARYL-METHYL]-HETEROBENZAMIDE, PREPARATION THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2010-09-23 | — | — | WO | disclosed |