Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 16/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817117 | 0.91 | ESR2 (0.55) | ESR2CYP2C9ESR1CYP3A4CYP2D6 | |
| SCHEMBL3811309 | 0.85 | ESR2 (0.60) | ESR2CYP2C9ESR1CYP3A4CYP2D6 | |
| SCHEMBL3816851 | 0.85 | ESR2 (0.60) | ESR2CYP2C9ESR1CYP3A4CYP2D6 | |
| SCHEMBL3811856 | 0.85 | ESR2 (0.60) | ESR2CYP2C9ESR1CYP3A4CYP2D6 | |
| SCHEMBL19677848 | 0.80 | CA2 (0.54) | CYP2C9CYP1A2CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL3807478 | 0.80 | CYP2C9 (0.56) | ESR2CYP2C9CYP1A2ESR1CYP3A4 | |
| SCHEMBL3809639 | 0.80 | CYP2C9 (0.56) | ESR2CYP2C9CYP1A2ESR1CYP3A4 | |
| SCHEMBL2718010 | 0.80 | CYP2C9 (0.56) | ESR2CYP2C9CYP1A2ESR1CYP3A4 | |
| SCHEMBL3811806 | 0.78 | ESR2 (0.45) | ESR2CYP2C9ESR1CYP3A4CYP2D6 | |
| SCHEMBL3826625 | 0.77 | ESR2 (0.46) | ESR2CYP2C9CYP1A2CYP2C19ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375461-B1 | DIPHENOL AND PROCESS FOR PRODUCING THE SAME | HONSHU CHEMICAL IND (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6872858-B2 | Diphenol and process for producing the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20040049086-A1 | Diphenol and process for producing the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049086-A1 | Diphenol and process for producing the same | CYP1A1, AHR, CYP2E1 | ESR2 940/4885CYP2C9 140/4885CYP1A2 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.