Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2586250 | 0.87 | EGLN1 (0.39) | EGLN1HIF1A | |
| SCHEMBL2579577 | 0.83 | EGLN1 (0.40) | EGLN1HIF1A | |
| SCHEMBL2586340 | 0.81 | EGLN1 (0.39) | EGLN1HIF1A | |
| SCHEMBL2578342 | 0.81 | WNT3A (0.41) | EGLN1HIF1A | |
| SCHEMBL2579550 | 0.81 | EGLN1 (0.40) | EGLN1HIF1A | |
| SCHEMBL2587868 | 0.80 | HIF1A (0.51) | EGLN1HIF1A | |
| SCHEMBL2581344 | 0.79 | EGLN1 (0.41) | EGLN1HIF1A | |
| SCHEMBL2579266 | 0.79 | HIF1A (0.48) | EGLN1HIF1A | |
| SCHEMBL2582020 | 0.78 | EGLN1 (0.41) | EGLN1HIF1A | |
| SCHEMBL2577065 | 0.77 | EGLN1 (0.45) | EGLN1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097416-A1 | AZAQUINOLONE BASED COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF | Amgen, Inc (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008076425-A1 | AZAQUINOLONE BASED COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF | AMGEN INC. (US) | 2008-06-26 | — | — | WO | disclosed |