Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824878 | 1.00 | MAOB (0.54) | MAOBNR4A2MRGPRX4SPHK2SPHK1 | |
| SCHEMBL3829423 | 1.00 | MAOB (0.54) | MAOBNR4A2MRGPRX4SPHK2SPHK1 | |
| SCHEMBL14487046 | 0.88 | KDM4E (0.57) | MAOBNR4A2NR4A1NR4A3KDM4E | |
| SCHEMBL14184546 | 0.88 | NR4A2 (0.57) | MAOBNR4A2MRGPRX4SPHK2SPHK1 | |
| SCHEMBL14487049 | 0.88 | KDM4E (0.57) | MAOBNR4A2NR4A1NR4A3KDM4E | |
| SCHEMBL3823938 | 0.88 | NR4A2 (0.57) | MAOBNR4A2MRGPRX4SPHK2SPHK1 | |
| SCHEMBL14184548 | 0.88 | NR4A2 (0.57) | MAOBNR4A2MRGPRX4SPHK2SPHK1 | |
| SCHEMBL4863258 | 0.88 | KDM4E (0.57) | MAOBNR4A2NR4A1NR4A3KDM4E | |
| SCHEMBL3823699 | 0.83 | CYP3A4 (0.46) | HIF1A | |
| SCHEMBL3826804 | 0.83 | CYP3A4 (0.46) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1793828-A4 | FIBRATE COMPOUNDS HAVING PPAR AGONIST ACTIVITY | REDDYS LAB LTD DR (IN) | 2009-09-02 | — | — | EP | disclosed |
| EP-1793828-A2 | FIBRATE COMPOUNDS HAVING PPAR AGONIST ACTIVITY | Dr. Reddy's Laboratories Ltd. (IN) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006029075-A2 | FIBRATE COMPOUNDS HAVING PPAR AGONIST ACTIVITY | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-03-16 | — | — | WO | disclosed |