Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14487046 | 1.00 | KDM4E (0.57) | KDM4EMEN1KMT2AMAPTMAOB | |
| SCHEMBL14487049 | 1.00 | KDM4E (0.57) | KDM4EMEN1KMT2AMAPTMAOB | |
| SCHEMBL3824878 | 0.88 | MAOB (0.54) | KDM4EMEN1KMT2AMAPTMAOB | |
| SCHEMBL3824575 | 0.88 | MAOB (0.54) | KDM4EMEN1KMT2AMAPTMAOB | |
| SCHEMBL3829423 | 0.88 | MAOB (0.54) | KDM4EMEN1KMT2AMAPTMAOB | |
| SCHEMBL5660644 | 0.88 | OPRK1 (0.60) | KDM4EMEN1KMT2AMAPTMAOB | |
| SCHEMBL4865374 | 0.87 | PPARG (0.61) | KDM4EMEN1KMT2AMAPTMAOB | |
| SCHEMBL5365883 | 0.87 | PPARG (0.61) | KDM4EMEN1KMT2AMAPTMAOB | |
| SCHEMBL5365583 | 0.87 | PPARG (0.61) | KDM4EMEN1KMT2AMAPTMAOB | |
| SCHEMBL14926312 | 0.85 | PPARG (0.48) | MEN1KMT2AMAPTPPARGNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045580-A1 | Novel Isoxazole Compounds Having Ppar Agonist Activity | DR REDDY'S LABORATORIES LIMITED (IN) | 2008-02-21 | — | — | US | disclosed |
| US-7230129-B2 | Process for the preparation of optically pure isomers of 2-(4-hydroxy phenoxy)-2-methyl-butyric acid methyl ester | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-06-12 | — | — | US | disclosed |
| US-20060194980-A1 | Process for the preparation of optically pure isomers of 2-(4-hydroxy phenoxy)-2-methyl-butyric acid methyl ester | DR. REDDY'S LABORATORIES LIMITED (IN) | 2006-08-31 | — | — | US | disclosed |
| WO-2006042245-A1 | NOVEL ISOXAZOLE COMPOUNDS HAVING PPAR AGONIST ACTIVITY | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045580-A1 | Novel Isoxazole Compounds Having Ppar Agonist Activity | PPARG, PPARA, PPARD | KDM4E 3723/4885MEN1 4842/4885KMT2A 3932/4885 |
| US-20060194980-A1 | Process for the preparation of optically pure isomers of 2-(4-hydroxy phenoxy)-2-methyl-butyric acid methyl ester | HBB, GABBR2, GABRB2 | KDM4E 32/4885MEN1 3285/4885KMT2A 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.