SCHEMBL3824865

SCHEMBL3824865

CC(=O)Oc1ccc(-c2ccccc2)c(O)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 3/20 0.63
NPC1 O15118 3/20 0.58
POLB P06746 1/20 0.58
CYP3A4 P08684 1/20 0.56
KDM4E B2RXH2 4/20 0.56
RAB9A P51151 2/20 0.56
MEN1 O00255 1/20 0.56
GLA P06280 1/20 0.56
KMT2A Q03164 1/20 0.56
MAPT P10636 5/20 0.55
ALDH1A1 P00352 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
ALOX5 P09917 1/20 0.53
ELANE P08246 1/20 0.51
GAA P10253 2/20 0.50
LMNA P02545 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPK1 P28482 1/20 0.50
EGFR P00533 1/20 0.49
HSP90AA1 P07900 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9510350 0.88 BACE1 (0.66) BACE1NPC1POLBCYP3A4KDM4E
SCHEMBL31273249 0.85 BACE1 (0.61) BACE1NPC1POLBKDM4ERAB9A
SCHEMBL9723788 0.83 BACE1 (0.59) BACE1NPC1POLBKDM4ERAB9A
SCHEMBL30701889 0.83 BACE1 (0.59) BACE1NPC1POLBCYP3A4KDM4E
SCHEMBL3790333 0.83 BACE1 (0.59) BACE1NPC1POLBCYP3A4KDM4E
SCHEMBL9903140 0.83 BACE1 (0.59) BACE1NPC1POLBKDM4ERAB9A
SCHEMBL30701890 0.83 BACE1 (0.59) BACE1NPC1POLBCYP3A4KDM4E
Acetone SCHEMBL28529251 0.83 BACE1 (0.60) BACE1NPC1CYP3A4KDM4ERAB9A
SCHEMBL8586897 0.82 BACE1 (0.61) BACE1NPC1POLBCYP3A4KDM4E
SCHEMBL29462754 0.82 ELANE (0.54) BACE1NPC1POLBKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109562033-A Cosmetic preparation for hair 花王株式会社 2019-04-02 CN disclosed
CN-109562034-A Hair cosmetic composition 花王株式会社 2019-04-02 CN disclosed
CN-106999382-A Hair deformation process agent 花王株式会社 2017-08-01 CN disclosed
CN-106999380-A Hair deforming agent 花王株式会社 2017-08-01 CN disclosed
US-20090086126-A1 Polarizing plate and liquid crystal display device using the same FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed