Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.41 |
| ▸ | FDPS | P14324 | 7/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.38 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594311 | 0.81 | PLA2G2C (0.50) | SMPD1FDPSGGPS1PLA2G2D | |
| SCHEMBL8472151 | 0.80 | PLA2G2C (0.41) | LPAR3LPAR1LPAR2SMPD1FDPS | |
| Phosphorylethanolamine SCHEMBL993264 | 0.80 | LPAR3 (0.44) | LPAR3LPAR1LPAR2LPAR5 | |
| SCHEMBL9115436 | 0.79 | PLA2G2C (0.43) | LPAR3LPAR1LPAR2SMPD1FDPS | |
| SCHEMBL10594234 | 0.78 | LPAR5 (0.50) | LPAR3LPAR1LPAR2SMPD1FDPS | |
| SCHEMBL2596151 | 0.78 | LPAR5 (0.50) | LPAR3LPAR1LPAR2SMPD1FDPS | |
| Phosphorylethanolamine SCHEMBL19412013 | 0.78 | LPAR3 (0.42) | LPAR3LPAR1LPAR2LPAR5 | |
| SCHEMBL302211 | 0.77 | FDPS (0.39) | FDPSGGPS1 | |
| SCHEMBL2039696 | 0.77 | FDPS (0.39) | FDPSGGPS1 | |
| Phosphorylethanolamine SCHEMBL28264156 | 0.76 | LPAR3 (0.64) | LPAR3LPAR1LPAR2LPAR5PLA2G2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086508-A2 | CATIONIC COLLOIDAL CARRIERS FOR DELIVERY OF ACTIVE AGENTS TO THE BLOOD-BRAIN BARRIER IN THE COURSE OF NEUROINFLAMMATORY DISEASES | MediGene Aktiengesellschaft (DE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008052766-A2 | CATIONIC COLLOIDAL CARRIERS FOR DELIVERY OF ACTIVE AGENTS TO THE BLOOD-BRAIN BARRIER IN THE COURSE OF NEUROINFLAMMATORY DISEASES | MEDIGENE AG (DE) | 2008-05-08 | — | — | WO | disclosed |