Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | ADK | P55263 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821913 | 0.91 | LMNA (0.76) | LMNAADKL3MBTL1ALDH1A1AHCY | |
| SCHEMBL3824213 | 0.90 | LMNA (0.75) | LMNAADKL3MBTL1P2RY2ALDH1A1 | |
| SCHEMBL3818845 | 0.90 | LMNA (0.75) | LMNAADKL3MBTL1P2RY2ALDH1A1 | |
| SCHEMBL3826637 | 0.90 | LMNA (0.75) | LMNAADKL3MBTL1P2RY2ALDH1A1 | |
| SCHEMBL3817582 | 0.90 | LMNA (0.75) | LMNAADKL3MBTL1ALDH1A1AHCY | |
| SCHEMBL3824216 | 0.90 | LMNA (0.75) | LMNAADKL3MBTL1P2RY2ALDH1A1 | |
| SCHEMBL3819223 | 0.90 | LMNA (0.75) | LMNAADKL3MBTL1P2RY2ALDH1A1 | |
| SCHEMBL3817720 | 0.90 | LMNA (0.73) | LMNAADKL3MBTL1ALDH1A1AHCY | |
| SCHEMBL3818943 | 0.89 | LMNA (0.72) | LMNAADK | |
| SCHEMBL3820400 | 0.89 | LMNA (0.72) | LMNAADKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882734-B1 | 5'-Deoxy-cytidine derivatives | HOFFMANN LA ROCHE (CH) | 2009-08-26 | — | — | EP | claimed |
| EP-0882734-A2 | 5'-Deoxy-cytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-12-09 | — | — | EP | claimed |
| EP-0882734-B1 | 5'-Deoxy-cytidine derivatives | HOFFMANN LA ROCHE (CH) | 2009-08-26 | — | — | EP | disclosed |
| US-6211166-B1 | COADMINISTERED WITH A 5-FLUOROURACIL DERIVATIVE; ANTICARCINOGENIC AGENTS | HOFFMAN-LA ROCHE INC. | 2001-04-03 | — | — | US | disclosed |
| EP-0882734-A2 | 5'-Deoxy-cytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1998-12-09 | — | — | EP | disclosed |