Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | NMT1 | P30419 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31603107 | 0.97 | MAPT (0.63) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL620359 | 0.97 | MAPT (0.63) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL30855071 | 0.93 | MAPT (0.61) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL18285426 | 0.90 | MAPT (0.55) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL29896399 | 0.90 | MAPT (0.55) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL618410 | 0.89 | MAPT (0.62) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL620990 | 0.88 | MAPT (0.53) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL1040706 | 0.88 | MAPT (0.54) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL620385 | 0.85 | NMT1 (0.53) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL6197990 | 0.84 | TP53 (0.63) | MAPTALDH1A1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796466-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-1796466-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006002047-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-01-05 | — | — | WO | disclosed |