Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 16/20 | 0.67 |
| ▸ | RARB | P10826 | 15/20 | 0.67 |
| ▸ | RARA | P10276 | 14/20 | 0.67 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382652 | 0.85 | RARG (0.80) | RARGRARBRARA | |
| Trifarotene SCHEMBL381493 | 0.81 | RARG (1.00) | RARGRARBRARA | |
| SCHEMBL382411 | 0.80 | RARG (0.98) | RARGRARBRARA | |
| SCHEMBL382275 | 0.79 | RARG (0.77) | RARGRARBRARAKMOMAP4K4 | |
| SCHEMBL382381 | 0.79 | RARG (0.67) | RARGRARBRARA | |
| SCHEMBL29763755 | 0.78 | RARG (0.81) | RARGRARBRARA | |
| SCHEMBL382535 | 0.78 | RARG (0.75) | RARGRARBRARAKDM4EALDH1A1 | |
| SCHEMBL382843 | 0.77 | RARG (1.00) | RARGRARBRARA | |
| SCHEMBL16737001 | 0.77 | RARG (0.70) | RARGRARBRARAALDH1A1PTPN11 | |
| SCHEMBL27337609 | 0.77 | RARG (0.85) | RARGRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | claimed |