SCHEMBL3825488

SCHEMBL3825488

NC[C@H]1CN(C(=O)O)C[C@H]1O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 4/20 0.39
GABRR2 P28476 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19211598 1.00 GABRR1 (0.39) GABRR1GABRR2
SCHEMBL19211618 1.00 GABRR1 (0.39) GABRR1GABRR2
SCHEMBL19211569 1.00 GABRR1 (0.39) GABRR1GABRR2
SCHEMBL3825326 1.00 GABRR1 (0.39) GABRR1GABRR2
SCHEMBL28249892 0.84 IDUA (0.30)
SCHEMBL3033289 0.82 GABRR1 (0.35) GABRR1GABRR2
SCHEMBL3276769 0.82 GABRR1 (0.35) GABRR1GABRR2
SCHEMBL3031676 0.82 GABRR1 (0.35) GABRR1GABRR2
SCHEMBL3033285 0.82 GABRR1 (0.35) GABRR1GABRR2
SCHEMBL5500989 0.82 GABRR1 (0.35) GABRR1GABRR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1796466-A4 ANTIBACTERIAL AGENTS GLAXO GROUP LTD (GB) 2009-09-02 EP disclosed
EP-2029612-A1 SUBSTITUTED 1-METHYL-1H-QUINOLIN-2-ONES AND 1-METHYL-1H-1,5-NAPHTHYRIDIN-2-ONES AS ANTIBACTERIALS Glaxo Group Limited (GB) 2009-03-04 EP disclosed
WO-2008006648-A1 SUBSTITUTED 1-METHYL-1H-QUINOLIN-2-ONES AND 1-METHYL-1H-1,5-NAPHTHYRIDIN-2-ONES AS ANTIBACTERIALS GLAXO GROUP LIMITED (GB) 2008-01-17 WO disclosed
EP-1796466-A2 ANTIBACTERIAL AGENTS GLAXO GROUP LIMITED (GB) 2007-06-20 EP disclosed
WO-2006002047-A2 ANTIBACTERIAL AGENTS GLAXO GROUP LIMITED (GB) 2006-01-05 WO disclosed