Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047414 | 0.85 | CHRM2 (0.38) | MAPTKMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL991996 | 0.85 | CHRM2 (0.38) | MAPTKMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL23274047 | 0.85 | CHRM2 (0.38) | MAPTKMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL23415469 | 0.84 | CHRM2 (0.37) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL23415565 | 0.84 | CHRM2 (0.37) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL23415467 | 0.84 | CHRM2 (0.37) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL25897057 | 0.82 | CHRM3 (0.36) | MAPTKMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL3825923 | 0.82 | CHRM3 (0.36) | MAPTKMT2ACHRM3CHRM2CHRM1 | |
| Lithium Ion SCHEMBL29888438 | 0.81 | CHRM3 (0.35) | MAPTKMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL30537611 | 0.81 | CHRM3 (0.35) | MAPTKMT2ACHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114980976-A | Covalent RAS inhibitors and uses thereof | 锐新医药公司 | 2022-08-30 | — | — | CN | disclosed |
| EP-2099747-A1 | RADIOLABELLING VIA FLUORINATION OF AZIRIDINES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008083729-A1 | RADIOLABELLING VIA FLUORINATION OF AZIRIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-17 | — | — | WO | disclosed |
| EP-1944288-A1 | Radiolabelling via fluorination of aziridines | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-07-16 | — | — | EP | disclosed |