SCHEMBL382619

SCHEMBL382619

CCN(C(C)=O)c1ccc(-c2cc(-c3ccc(OC(=O)O)cc3)ccc2CCCO)cc1C(C)(C)C

nearest known ligand 0.78

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RARG P13631 19/20 0.78
RARA P10276 18/20 0.78
RARB P10826 18/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL382215 0.90 RARG (0.77) RARGRARARARB
SCHEMBL382095 0.88 RARG (1.00) RARGRARARARB
SCHEMBL383257 0.87 RARG (0.81) RARGRARARARB
SCHEMBL381768 0.85 RARG (0.80) RARGRARARARB
SCHEMBL382732 0.81 RARG (0.65) RARGRARARARB
SCHEMBL383570 0.80 RARG (0.62) RARGRARARARB
SCHEMBL382828 0.79 RARG (0.61) RARGRARARARB
SCHEMBL13196065 0.78 RARG (0.80) RARGRARARARB
SCHEMBL382407 0.77 RARG (0.60) RARGRARARARB
SCHEMBL381582 0.77 RARG (1.00) RARGRARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1831149-B1 NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS GALDERMA RES & DEV (FR) 2012-01-25 EP claimed