Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 14/20 | 0.62 |
| ▸ | RARA | P10276 | 13/20 | 0.62 |
| ▸ | RARB | P10826 | 13/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382828 | 0.90 | RARG (0.61) | RARGRARARARBALDH1A1 | |
| SCHEMBL382215 | 0.89 | RARG (0.77) | RARGRARARARB | |
| SCHEMBL382137 | 0.89 | RARG (0.79) | RARGRARARARBHRH3 | |
| SCHEMBL382341 | 0.87 | RARB (0.63) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL382732 | 0.87 | RARG (0.65) | RARGRARARARB | |
| SCHEMBL382560 | 0.86 | RARG (0.62) | RARGRARARARBHRH3KDM4E | |
| SCHEMBL382538 | 0.86 | RARG (0.67) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL383420 | 0.86 | RARB (0.62) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL382273 | 0.85 | RARG (0.64) | RARGRARARARBHRH3KDM4E | |
| SCHEMBL382683 | 0.80 | RARG (0.78) | RARGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831149-B1 | NOVEL LIGANDS THAT MODULATE RAR RECEPTORS AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2012-01-25 | — | — | EP | claimed |