Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384303 | 1.00 | ALOX5 (0.63) | ALOX5SLC2A1RELAKDM4ERAB9A | |
| SCHEMBL14281079 | 0.97 | ALOX5 (0.66) | ALOX5SLC2A1RELAKDM4ERAB9A | |
| SCHEMBL29627557 | 0.92 | ALOX5 (0.55) | ALOX5SLC2A1RELAKDM4ERAB9A | |
| SCHEMBL10895222 | 0.89 | ALOX5 (0.54) | ALOX5KDM4ERAB9ANPC1HPGD | |
| SCHEMBL10784846 | 0.89 | ALOX5 (0.54) | ALOX5KDM4ERAB9ANPC1HPGD | |
| SCHEMBL23517134 | 0.88 | ALOX5 (0.77) | ALOX5SLC2A1KDM4ERAB9ANPC1 | |
| SCHEMBL10330358 | 0.86 | ALOX5 (0.70) | ALOX5SLC2A1KDM4ERAB9ANPC1 | |
| SCHEMBL10925339 | 0.86 | ALOX5 (0.63) | ALOX5SLC2A1KDM4ERAB9ANPC1 | |
| SCHEMBL10784853 | 0.86 | ALOX5 (0.51) | ALOX5KDM4ERAB9ANPC1PKM | |
| SCHEMBL1077058 | 0.83 | ALOX5 (0.47) | ALOX5SLC2A1KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240189217-A1 | SUNSCREEN COMPOSITION INCLUDING A FLUORESCENT AGENT EXCITABLE BY AN ULTRAVIOLET LAM | SHULMAN ZACHARY (US) | 2024-06-13 | — | — | US | claimed |
| US-20190294069-A1 | SECURITY LIQUID ELECTROSTATIC INK COMPOSITION | HEWLETT-PACKARD INDIGO B.V. (NL) | 2019-09-26 | — | — | US | claimed |
| EP-2289893-B1 | Haloaryl substituted aminopurines for use in treatment | SIGNAL PHARM LLC (US) | 2014-06-25 | — | — | EP | claimed |
| US-8680076-B2 | Methods of treatment, improvement and prevention using haloaryl substituted aminopurines | SIGNAL PHARMACEUTICALS, LLC (US) | 2014-03-25 | — | — | US | claimed |
| EP-2112151-B1 | Haloaryl substituted aminopurines for use in treatment | SIGNAL PHARM LLC (US) | 2013-11-20 | — | — | EP | claimed |
| US-8440661-B2 | Methods of modulating inflammatory cell recruitment and gene expression using haloaryl substituted aminopurines | SIGNAL PHARMACEUTICALS, LLC (US) | 2013-05-14 | — | — | US | claimed |
| EP-2010186-B1 | HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2012-12-26 | — | — | EP | claimed |
| US-20120129807-A1 | METHODS OF TREATMENT, IMPROVEMENT AND PREVENTION USING HALOARYL SUBSTITUTED AMINOPURINES | SIGNAL PHARMACEUTICALS, LLC | 2012-05-24 | — | — | US | claimed |
| EP-2289893-A1 | Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith | Signal Pharmaceuticals LLC (US) | 2011-03-02 | — | — | EP | claimed |
| EP-1610954-B1 | METHOD FOR RECORDING INFORMATION IN LUMINESCENT COMPOSITIONS AND USES THEREOF IN ARTICLES OF MANUFACTURE | AMERICAN DYE SOURCE INC (CA) | 2010-11-17 | — | — | EP | claimed |
| EP-1240246-A1 | NON-EXUDING OPTICALLY BRIGHTENED POLYOLEFIN BLENDS | EASTMAN CHEMICAL COMPANY (US) | 2002-09-18 | — | — | EP | claimed |
| US-6312822-B1 | AS POLAR ADDITIVES POLYMERIC ESTERS, OLIGOMERIC ESTERS, POLYAMIDES, FATTY ACIDS AMIDES OF ALIPHATIC AMINES AND DIAMINES, COPOLYMERS OF POLY(ETHYLENE-COACRYLIC ACID), OR ESTERS OF POLY(ALKYLENE GLYCOLS) | EASTMAN CHEM CO (US) | 2001-11-06 | — | — | US | claimed |
| WO-2001036533-A1 | NON-EXUDING OPTICALLY BRIGHTENED POLYOLEFIN BLENDS | EASTMAN CHEMICAL COMPANY (US) | 2001-05-25 | — | — | WO | claimed |
| EP-1099137-A1 | DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS | EASTMAN CHEMICAL COMPANY (US) | 2001-05-16 | — | — | EP | claimed |
| WO-1999061955-A1 | DISPERSION AIDS FOR OPTICAL BRIGHTENERS IN POLYOLEFINS | EASTMAN CHEMICAL COMPANY (US) | 1999-12-02 | — | — | WO | claimed |
| US-5985389-A | POLESTER OR POLYAMIDEESTER ACETALDEHYDE REDUCING COMPOUND; FOOD AND BEVERAGE CONTAINERS; CLARITY | EASTMAN CHEMICAL COMPANY (US) | 1999-11-16 | — | — | US | claimed |
| EP-0045279-B1 | AMINE OXIDE COMPOUNDS, PROCESSES FOR THEIR MANUFACTURE AND THEIR USE AS OPTICAL BRIGHTENERS | CIBA-GEIGY AG (CH) | 1988-06-01 | — | — | EP | claimed |
| EP-0029003-B1 | SALTS OF CATIONIC BRIGHTENERS, THEIR PREPARATION AND THEIR USE ON ORGANIC MATERIALS AS WELL AS THEIR CONCENTRATED AQUEOUS SOLUTIONS | CIBA-GEIGY AG (CH) | 1984-12-05 | — | — | EP | claimed |
| EP-0045279-A1 | Amine oxide compounds, processes for their manufacture and their use as optical brighteners | CIBA-GEIGY AG (CH) | 1982-02-03 | — | — | EP | claimed |
| EP-0029003-A2 | Salts of cationic brighteners, their preparation and their use on organic materials as well as their concentrated aqueous solutions | CIBA-GEIGY AG (CH) | 1981-05-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129807-A1 | METHODS OF TREATMENT, IMPROVEMENT AND PREVENTION USING HALOARYL SUBSTITUTED AMINOPURINES | TPMT, MGMT, UNG | ALOX5 681/4885SLC2A1 3158/4885RELA 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.