Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | DCK | P27707 | 6/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831479 | 0.79 | GRM5 (0.45) | RETDCKSCDGRM5 | |
| SCHEMBL3847667 | 0.77 | DCK (0.46) | RETDCKSCD | |
| SCHEMBL14130746 | 0.77 | RET (0.44) | RETDCKSCDGPR6 | |
| SCHEMBL3828744 | 0.74 | DCK (0.46) | RETDCKSCD | |
| SCHEMBL3826351 | 0.72 | RET (0.42) | RETDCKGPR6GRM5SCN9A | |
| SCHEMBL3832548 | 0.72 | RET (0.42) | RETDCKGPR6GRM5SCN9A | |
| SCHEMBL14143777 | 0.68 | SCD (0.52) | RETDCKSCDGPR6 | |
| SCHEMBL3831437 | 0.68 | CYP3A4 (0.42) | SCD | |
| SCHEMBL3854486 | 0.67 | CYP3A4 (0.41) | SCD | |
| SCHEMBL3826490 | 0.67 | SCD (0.46) | DCKSCDGPR6SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099755-A2 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | Glenmark Pharmaceuticals S.A. (CH) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008062276-A2 | ACETYLENE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-05-29 | — | — | WO | disclosed |